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Pathology · USMLE Step 1 · Healthcare and Nursing

USMLE Pathology: Musculoskeletal and Dermatologic System

Bone tumor morphology, connective tissue disease histology, and classic skin biopsy findings, one finding per card.

About this set

39 basic cards for USMLE Step 1 Pathology. Set 14 of 27 in USMLE Pathology. It opens with "Which bone tumor classically shows a Codman triangle on X-ray?" and "What X-ray pattern of periosteal new bone formation is classic for osteosarcoma?". Study it alongside the other USMLE Step 1 sets below.

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Which bone tumor classically shows a Codman triangle on X-ray?
Show answerOsteosarcoma
What X-ray pattern of periosteal new bone formation is classic for osteosarcoma?
Show answerSunburst pattern
Osteosarcoma most commonly arises in which part of a long bone?
Show answerThe metaphysis, often around the knee
What is the most common benign bone tumor?
Show answerOsteochondroma
What small, painful bone lesion has a central nidus and improves with NSAIDs?
Show answerOsteoid osteoma
A 'soap bubble' lytic lesion in the epiphysis near the knee suggests which tumor?
Show answerGiant cell tumor of bone
What characteristic cell type gives giant cell tumor of bone its name?
Show answerMultinucleated osteoclast-like giant cells
What periosteal reaction pattern on X-ray is classic for Ewing sarcoma?
Show answerOnion-skin (lamellated) periosteal reaction
Ewing sarcoma is composed histologically of ____.
Show answersmall round blue cells
What chromosomal translocation is characteristic of Ewing sarcoma?
Show answert(11;22)
What is the malignant cartilage-forming bone tumor called?
Show answerChondrosarcoma
What benign tumor of hyaline cartilage arises within the medullary cavity, often in the hands?
Show answerEnchondroma
What bone lesion shows a 'ground glass' appearance on X-ray?
Show answerFibrous dysplasia
In fibrous dysplasia, the woven bone trabeculae have a histologic pattern described as ____.
Show answerChinese letters
In SLE, concentric periarterial fibrosis in the spleen produces what classic finding?
Show answerOnion-skin lesions

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