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Pathology · USMLE Step 1 · Healthcare and Nursing

USMLE Pathology: Pulmonary System

Gross and microscopic lung pathology including obstructive versus restrictive disease patterns, pneumonia types, and pulmonary vascular disease. Original cards testing the underlying concepts.

About this set

40 basic cards for USMLE Step 1 Pathology. Set 19 of 27 in USMLE Pathology. It opens with "PFT hallmark of obstructive lung disease" and "Two diseases that together make up COPD". Study it alongside the other USMLE Step 1 sets below.

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PFT hallmark of obstructive lung disease
Show answerDecreased FEV1/FVC ratio
Two diseases that together make up COPD
Show answerChronic bronchitis and emphysema
Clinical definition of chronic bronchitis
Show answerProductive cough for at least 3 months in each of 2 consecutive years
In chronic bronchitis, does the Reid index increase or decrease?
Show answerIncreases
Most common cause of centriacinar emphysema
Show answerCigarette smoking
Panacinar emphysema is classically associated with which deficiency
Show answerAlpha-1 antitrypsin deficiency
Mechanism of alveolar wall destruction in alpha-1 antitrypsin deficiency
Show answerUnopposed neutrophil elastase destroys elastin in the alveolar walls
Asthma is classically what type of hypersensitivity reaction
Show answerType I (IgE-mediated) hypersensitivity
Definition of bronchiectasis
Show answerPermanent dilation of bronchi and bronchioles caused by chronic necrotizing infection or inflammation
PFT hallmark of restrictive lung disease
Show answerDecreased total lung capacity with a normal or increased FEV1/FVC ratio
Two general categories of restrictive lung disease
Show answerPoor chest wall or neuromuscular mechanics, and interstitial lung disease
Histologic pattern classically seen in idiopathic pulmonary fibrosis
Show answerUsual interstitial pneumonia (UIP)
Characteristic gross lung finding in idiopathic pulmonary fibrosis
Show answerHoneycomb lung
Definition of pneumoconiosis
Show answerInterstitial lung fibrosis caused by inhalation of occupational dusts or particles
Silicosis produces what characteristic finding in the hilar lymph nodes
Show answerEggshell calcification

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