Gross and microscopic lung pathology including obstructive versus restrictive disease patterns, pneumonia types, and pulmonary vascular disease. Original cards testing the underlying concepts.
40 cards · basic cards · AI-written, checked twice. Edit anything.
- PFT hallmark of obstructive lung disease
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Decreased FEV1/FVC ratio
- Two diseases that together make up COPD
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Chronic bronchitis and emphysema
- Clinical definition of chronic bronchitis
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Productive cough for at least 3 months in each of 2 consecutive years
- In chronic bronchitis, does the Reid index increase or decrease?
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Increases
- Most common cause of centriacinar emphysema
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Cigarette smoking
- Panacinar emphysema is classically associated with which deficiency
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Alpha-1 antitrypsin deficiency
- Mechanism of alveolar wall destruction in alpha-1 antitrypsin deficiency
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Unopposed neutrophil elastase destroys elastin in the alveolar walls
- Asthma is classically what type of hypersensitivity reaction
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Type I (IgE-mediated) hypersensitivity
- Definition of bronchiectasis
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Permanent dilation of bronchi and bronchioles caused by chronic necrotizing infection or inflammation
- PFT hallmark of restrictive lung disease
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Decreased total lung capacity with a normal or increased FEV1/FVC ratio
- Two general categories of restrictive lung disease
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Poor chest wall or neuromuscular mechanics, and interstitial lung disease
- Histologic pattern classically seen in idiopathic pulmonary fibrosis
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Usual interstitial pneumonia (UIP)
- Characteristic gross lung finding in idiopathic pulmonary fibrosis
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Honeycomb lung
- Definition of pneumoconiosis
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Interstitial lung fibrosis caused by inhalation of occupational dusts or particles
- Silicosis produces what characteristic finding in the hilar lymph nodes
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Eggshell calcification