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Pathology · USMLE Step 1

USMLE Pathology: Ophthalmic

Eye pathology morphology including cataracts, glaucoma, and retinal disease, one finding per card.

32 cards · basic cards · AI-written, checked twice. Edit anything.

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What is a cataract?
Opacification of the lens
What is the most common cause of cataracts?
Aging (senile cataract)
What causes cataracts in diabetes mellitus?
Osmotic damage from sorbitol accumulation in the lens
What causes cataracts in galactosemia?
Galactitol accumulation in the lens
What congenital infection classically causes cataracts?
Congenital rubella infection
What type of cataract is associated with prolonged corticosteroid use?
Posterior subcapsular cataract
What chromosomal disorder is associated with early cataracts?
Down syndrome (trisomy 21)
What is the most common type of glaucoma?
Primary open-angle glaucoma
What is the underlying mechanism of open-angle glaucoma?
Increased resistance to aqueous humor outflow through the trabecular meshwork
What is the underlying mechanism of angle-closure glaucoma?
The iris blocks the anterior chamber drainage angle, obstructing aqueous outflow
Which race is at increased risk for primary open-angle glaucoma?
African American
What optic disc finding is seen in glaucoma?
Increased cupping of the optic disc (increased cup-to-disc ratio)
What visual field pattern results from chronic glaucoma?
Progressive peripheral vision loss leading to tunnel vision
What class of drugs can precipitate acute angle-closure glaucoma?
Anticholinergics
What are the two types of diabetic retinopathy?
Nonproliferative and proliferative

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