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Embryology · USMLE Step 1

USMLE Embryology: Placenta and Fetal Membranes

Placental development, umbilical cord structures, amnion and chorion, and twinning types tested on USMLE Step 1.

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Which trophoblast layer is the inner, mononuclear, mitotically active layer?
Cytotrophoblast
Which trophoblast layer is the outer, invasive, multinucleated layer?
Syncytiotrophoblast
Which trophoblast layer secretes hCG?
Syncytiotrophoblast
The cytotrophoblast gives rise to which other trophoblast layer?
Syncytiotrophoblast
What is the maternal (decidual) component of the placenta called?
Decidua basalis
What is the decidua that covers the implanted conceptus, facing the uterine lumen, called?
Decidua capsularis
What is the decidua lining the rest of the uterine cavity, away from the implantation site, called?
Decidua parietalis
Fusion of the decidua capsularis with the decidua parietalis obliterates what space?
The uterine cavity (uterine lumen)
What is the villous portion of the chorion that forms the fetal part of the placenta called?
Chorion frondosum
What is the smooth, villus-free portion of the chorion called?
Chorion laeve
What villi anchor the placenta to the decidua basalis?
Anchoring (cytotrophoblastic) villi
The ____ carries oxygenated blood from the placenta to the fetus.
umbilical vein
The ____ carry deoxygenated blood from the fetus to the placenta.
umbilical arteries
What gelatinous connective tissue surrounds and protects the umbilical vessels?
Wharton's jelly
How many vessels does a normal umbilical cord contain?
Three (two arteries and one vein)

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