Neural tube formation and closure timing paired with the neural tube defect that results when each step fails.
About this set
35 basic cards for USMLE Step 1 Embryology. Set 8 of 11 in USMLE Embryology. It opens with "What is the process called by which the neural plate folds into the neural tube?" and "What embryonic structure induces the overlying ectoderm to become neuroectoderm?". Study it alongside the other USMLE Step 1 sets below.
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- What is the process called by which the neural plate folds into the neural tube?
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Neurulation- What embryonic structure induces the overlying ectoderm to become neuroectoderm?
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The notochord- In approximately what gestational week does neurulation begin?
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Week 3- What flat structure of thickened neuroectoderm is the first visible sign of neural tube formation?
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The neural plate- What paired elevations flank the neural groove as the neural plate invaginates?
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The neural folds- The neural tube begins closing near the ____ region and proceeds in both cranial and caudal directions like a zipper.
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cervical- On approximately what day of development does the anterior (rostral) neuropore close?
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Day 25- On approximately what day of development does the posterior (caudal) neuropore close?
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Day 27 to 28- Failure of closure of the anterior neuropore causes what neural tube defect?
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Anencephaly- Failure of closure of the posterior neuropore causes what category of neural tube defect?
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Spina bifida- In anencephaly, what happens to the forebrain tissue that is left exposed without covering neural tube?
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It degenerates in utero- What maternal condition often accompanies anencephaly, due to the fetus's impaired swallowing reflex?
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Polyhydramnios- What is the mildest form of spina bifida, in which the vertebral arch fails to close but no tissue herniates?
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Spina bifida occulta- What cutaneous finding often overlies spina bifida occulta?
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A tuft of hair or a skin dimple over the lower back- What term describes herniation of the meninges alone, without neural tissue, through a vertebral defect?
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Meningocele
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