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Embryology · USMLE Step 1 · Healthcare and Nursing

USMLE Embryology: Early Development and Germ Layers

Fertilization through gastrulation, the three germ layers, and their tissue derivatives, one fact per card.

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34 basic cards for USMLE Step 1 Embryology. Set 4 of 11 in USMLE Embryology. It opens with "Fertilization normally occurs in the ____ of the uterine (fallopian) tube" and "What reaction alters the zona pellucida immediately after fertilization to". Study it alongside the other USMLE Step 1 sets below.

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Fertilization normally occurs in the ____ of the uterine (fallopian) tube.
Show answerampulla
What reaction alters the zona pellucida immediately after fertilization to block additional sperm from entering the oocyte?
Show answerThe cortical (zona) reaction.
What is the chromosome number of a normal human zygote?
Show answer46, diploid (2N).
What term describes the rapid mitotic divisions of the zygote that occur without an overall increase in size?
Show answerCleavage.
What solid ball of blastomeres results from cleavage?
Show answerThe morula.
Around what day after fertilization does the morula enter the uterine cavity?
Show answerDay 3 to 4.
What is the fluid-filled cavity that forms inside the morula, converting it into a blastocyst?
Show answerThe blastocele (blastocyst cavity).
Which outer cell layer of the blastocyst gives rise to the placenta?
Show answerThe trophoblast.
Which cluster of cells inside the blastocyst gives rise to the embryo proper?
Show answerThe inner cell mass (embryoblast).
Around what day after fertilization does implantation of the blastocyst into the endometrium occur?
Show answerDay 6.
Into which two layers does the trophoblast differentiate?
Show answerCytotrophoblast and syncytiotrophoblast.
Which trophoblast layer is mitotically active and retains distinct cell boundaries?
Show answerThe cytotrophoblast.
Which trophoblast layer is invasive, lacks distinct cell boundaries, and secretes hCG?
Show answerThe syncytiotrophoblast.
hCG secreted by the syncytiotrophoblast maintains which ovarian structure during early pregnancy?
Show answerThe corpus luteum.
During week 2, the inner cell mass reorganizes into a bilaminar germ disc made of which two layers?
Show answerEpiblast and hypoblast.

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