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Embryology · USMLE Step 1

USMLE Embryology: Branchial (Pharyngeal) Apparatus

Pharyngeal arch, pouch, and cleft derivatives and their associated congenital defects tested on USMLE Step 1.

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Which cartilage gives rise to skeletal structures of the 1st pharyngeal arch?
Meckel's cartilage
Which cranial nerve supplies the 1st pharyngeal arch?
CN V (trigeminal), mainly the mandibular division V3
Which two ear ossicles derive from the 1st pharyngeal arch?
Malleus and incus
What major muscle group derives from the 1st pharyngeal arch?
Muscles of mastication
Which facial bone derives from 1st arch cartilage?
Mandible
Which 1st arch muscle dampens sound by tensing the tympanic membrane?
Tensor tympani
Which cartilage gives rise to skeletal structures of the 2nd pharyngeal arch?
Reichert's cartilage
Which cranial nerve supplies the 2nd pharyngeal arch?
CN VII (facial)
Which ear ossicle derives from the 2nd pharyngeal arch?
Stapes
What major muscle group derives from the 2nd pharyngeal arch?
Muscles of facial expression
Which cranial nerve supplies the 3rd pharyngeal arch?
CN IX (glossopharyngeal)
Which skeletal structure derives from the 3rd pharyngeal arch?
Greater horn and lower body of the hyoid bone
Which muscle derives from the 3rd pharyngeal arch?
Stylopharyngeus
Which branch of CN X supplies the 4th pharyngeal arch?
Superior laryngeal nerve
Which muscles derive from the 4th pharyngeal arch?
Pharyngeal constrictors and cricothyroid

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