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Pharmacology · USMLE Step 1 · Healthcare and Nursing

USMLE Pharmacology: Respiratory Drugs

Bronchodilators and leukotriene inhibitors with mechanism of action and one signature side effect per card, distinct from the clinical inhaler-technique focus of the Nursing Pharmacology respiratory deck.

About this set

40 mixed cards for USMLE Step 1 Pharmacology. Set 17 of 19 in USMLE Pharmacology. It opens with "What drug class does albuterol belong to?" and "Mechanism of action of albuterol". Study it alongside the other USMLE Step 1 sets below.

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What drug class does albuterol belong to?
Show answerShort-acting beta-2 agonist (SABA)
Mechanism of action of albuterol
Show answerBinds beta-2 adrenergic receptors, activating adenylyl cyclase to raise cAMP and relax bronchial smooth muscle
Signature side effect of albuterol
Show answerTremor and tachycardia
Why can beta-2 agonists like albuterol cause hypokalemia?
Show answerThey stimulate the Na+/K+-ATPase, driving potassium into cells
Levalbuterol is what relative to albuterol?
Show answerThe R-enantiomer of albuterol
What drug class is salmeterol?
Show answerLong-acting beta-2 agonist (LABA)
Why is salmeterol not used to abort an acute asthma attack?
Show answerIt has a slow onset of action
How does formoterol differ from salmeterol in onset?
Show answerFormoterol has a rapid onset of action despite being a LABA
Black box warning for LABAs used as monotherapy in asthma
Show answerIncreased risk of asthma-related death without a concurrent inhaled corticosteroid
Off-label obstetric use of terbutaline
Show answerTocolysis, to delay preterm labor
Beta-2 agonists relax bronchial smooth muscle by activating ____, which raises intracellular cAMP.
Show answeradenylyl cyclase
SABA
Show answerShort-acting beta-2 agonist
LABA
Show answerLong-acting beta-2 agonist
What drug class is ipratropium?
Show answerShort-acting muscarinic antagonist (SAMA)
Mechanism of action of ipratropium
Show answerAntagonizes M3 muscarinic receptors in bronchial smooth muscle, blocking acetylcholine-induced bronchoconstriction

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