Common sexually transmitted infections with their causative organism, hallmark presentation, and first-line treatment tested on USMLE Step 1.
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- What is the Gram stain morphology of Neisseria gonorrhoeae?
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Gram-negative diplococci- What type of discharge is classic for gonorrhea?
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Purulent, thick, yellow-green discharge- First-line treatment for gonorrhea?
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Ceftriaxone (intramuscular)- What is notable about the typical presentation of Chlamydia trachomatis infection?
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Often asymptomatic, especially in women- First-line treatment for Chlamydia trachomatis infection?
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Doxycycline- Which Chlamydia trachomatis serovars cause lymphogranuloma venereum?
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L1, L2, and L3- What is the classic clinical progression of lymphogranuloma venereum?
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A small painless genital ulcer followed by painful, matted inguinal lymphadenopathy (buboes)- Treponema pallidum
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Syphilis- What is the hallmark lesion of primary syphilis?
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A painless genital chancre- What is the classic rash distribution in secondary syphilis?
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A maculopapular rash involving the palms and soles- What are condylomata lata?
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Flat, wart-like lesions seen in secondary syphilis- What are gummas?
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Granulomatous lesions seen in tertiary syphilis- What neurologic complication of tertiary syphilis affects the dorsal columns of the spinal cord?
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Tabes dorsalis- What cardiovascular complication is associated with tertiary syphilis?
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Syphilitic aortitis, which can cause a thoracic aortic aneurysm- Name the nontreponemal screening tests for syphilis.
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VDRL and RPR
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