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Musculoskeletal and Dermatology · USMLE Step 1

USMLE Dermatology: Skin Lesion Recognition

Classic skin lesion morphology (macule, papule, vesicle, plaque) matched to the disease it signals, one lesion per card.

40 cards · basic cards · AI-written, checked twice. Edit anything.

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Classic skin lesion in herpes simplex virus infection?
Grouped vesicles on an erythematous base
Dew drops on a rose petal appearance of vesicles is classic for which disease?
Varicella (chickenpox)
Classic skin lesion in psoriasis?
Well-demarcated plaques with silvery-white scale
An expanding annular erythematous patch with central clearing (erythema migrans) signals which disease?
Lyme disease
Classic skin lesion in tinea corporis (ringworm)?
Annular plaque with a raised, scaly border and central clearing
Classic skin lesion in molluscum contagiosum?
Umbilicated, flesh-colored papules
Classic primary skin lesion in acne vulgaris?
Comedones (open, blackhead, or closed, whitehead)
Classic skin lesion of seborrheic keratosis?
A 'stuck-on' waxy, warty plaque
Classic skin lesion of actinic keratosis?
A rough, scaly papule on sun-exposed skin
Classic skin lesion of basal cell carcinoma?
A pearly papule with rolled borders and telangiectasias
Classic skin lesion of squamous cell carcinoma?
A scaly, ulcerated papule or plaque on sun-exposed skin
Classic skin lesion of melanoma?
An asymmetric pigmented macule or papule with irregular borders
Classic skin lesion in urticaria (hives)?
Transient, pruritic, edematous wheals
Target (iris) lesions are the classic skin finding in which condition?
Erythema multiforme
Classic skin lesion in pemphigus vulgaris?
Flaccid bullae with a positive Nikolsky sign

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