Reproductive endocrinology, menstrual cycle physiology, and classic reproductive tract pathology tested on USMLE Step 1.
40 cards · basic cards · AI-written, checked twice. Edit anything.
- Where is GnRH secreted from?
- The hypothalamus (arcuate nucleus)
- What happens to gonadotropin release with continuous, non-pulsatile GnRH administration?
- It is suppressed (downregulates GnRH receptors)
- What is the primary action of FSH on the ovarian follicle?
- Stimulates granulosa cell growth and estrogen production
- What hormonal event triggers ovulation?
- The LH surge
- In the two cell, two gonadotropin model, ____ cells produce androgens in response to LH stimulation.
- theca
- Granulosa cells convert androgens into estrogen using the enzyme ____, under FSH stimulation.
- aromatase
- Which hormone dominates the follicular phase of the menstrual cycle?
- Estrogen, from the dominant follicle
- Which hormone dominates the luteal phase of the menstrual cycle?
- Progesterone, from the corpus luteum
- What effect does progesterone have on the endometrium?
- Converts it to a secretory, glandular state
- What effect does estrogen have on the endometrium?
- Drives proliferation of glands and stroma
- What happens to basal body temperature after ovulation?
- It rises, due to progesterone
- What hormone maintains the corpus luteum in early pregnancy?
- hCG, human chorionic gonadotropin
- What cell type produces hCG?
- Syncytiotrophoblast
- What is the function of inhibin B?
- Inhibits FSH secretion (from granulosa cells in females, Sertoli cells in males)
- How does prolactin affect the reproductive axis?
- Inhibits GnRH release, causing lactational amenorrhea