Cholinergic, adrenergic, and autonomic blocking drugs with receptor target and one signature clinical effect per card.
38 cards · mixed cards · AI-written, checked twice. Edit anything.
- Bethanechol: receptor target and main clinical use?
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Muscarinic receptor agonist; used for postoperative/neurogenic ileus and urinary retention- Pilocarpine: receptor target and main clinical use?
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Muscarinic receptor agonist; used to treat open-angle glaucoma and xerostomia- Methacholine, a muscarinic receptor agonist, is used in a bronchial challenge test to help diagnose ____.
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asthma- Carbachol: receptor target and main clinical use?
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Muscarinic and nicotinic receptor agonist; produces miosis in glaucoma and eye surgery- Nicotine: receptor target?
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Nicotinic acetylcholine receptor agonist at autonomic ganglia and the neuromuscular junction- Physostigmine: mechanism and signature clinical use?
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Acetylcholinesterase inhibitor that crosses the blood brain barrier; antidote for anticholinergic (atropine) toxicity- Neostigmine: mechanism and signature clinical use?
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Acetylcholinesterase inhibitor that does not cross the blood brain barrier; used for postoperative ileus, urinary retention, and reversal of neuromuscular blockade- Pyridostigmine: mechanism and signature clinical use?
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Acetylcholinesterase inhibitor; used for long-term maintenance treatment of myasthenia gravis- The historic Tensilon test used the short-acting acetylcholinesterase inhibitor ____ to help diagnose myasthenia gravis.
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edrophonium- Donepezil: mechanism and signature clinical use?
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Acetylcholinesterase inhibitor; used to treat Alzheimer disease- Organophosphate poisoning irreversibly inhibits acetylcholinesterase, producing a cholinergic toxidrome treated with atropine plus ____.
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pralidoxime- Pralidoxime: mechanism of action in organophosphate poisoning?
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Regenerates acetylcholinesterase by cleaving the phosphate bond, most effective before enzyme aging occurs- Atropine used as a toxicology antidote: receptor target and indication?
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Muscarinic receptor antagonist; antidote for cholinergic toxicity such as organophosphate poisoning- Atropine used to treat symptomatic bradycardia: receptor target?
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Muscarinic receptor antagonist (blocks vagal tone on the SA node)- Benztropine: receptor target and clinical use?
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Muscarinic receptor antagonist; treats Parkinson disease symptoms and antipsychotic-induced extrapyramidal side effects
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