Anesthetics, antiepileptics, antidepressants, and antipsychotics with mechanism and one signature side effect per card.
About this set
45 mixed cards for USMLE Step 1 Pharmacology. Set 6 of 19 in USMLE Pharmacology. It opens with "What is the mechanism of action of nitrous oxide as a general anesthetic?" and "Nitrous oxide can cause ____ if 100% oxygen is not given at the end of". Study it alongside the other USMLE Step 1 sets below.
45 cards · mixed cards · AI-written, checked twice. Edit anything.
- What is the mechanism of action of nitrous oxide as a general anesthetic?
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NMDA receptor antagonist
- Nitrous oxide can cause ____ if 100% oxygen is not given at the end of anesthesia.
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diffusion hypoxia
- What is the signature toxicity of halothane?
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Hepatotoxicity (halothane hepatitis)
- Malignant hyperthermia is triggered by volatile anesthetics or succinylcholine in patients with a ____ gene mutation.
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RYR1
- What drug is used to treat malignant hyperthermia?
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Dantrolene
- What is the mechanism of action of propofol?
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Potentiates GABA-A receptor activity
- What is a signature side effect of propofol?
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Hypotension from myocardial depression
- What is the mechanism of action of ketamine?
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NMDA receptor antagonist
- What signature side effect is associated with ketamine?
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Emergence delirium (hallucinations on awakening)
- What is a signature side effect of etomidate?
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Adrenocortical suppression
- What is the mechanism of action of local anesthetics?
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Block voltage-gated sodium channels from the intracellular side
- Ester-type local anesthetics are metabolized by plasma cholinesterase, while ____-type local anesthetics are metabolized by the liver.
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amide
- What is the mechanism of action of phenytoin?
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Blocks voltage-gated sodium channels (use-dependent)
- What signature side effect is associated with phenytoin?
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Gingival hyperplasia
- What is the mechanism of action of carbamazepine?
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Blocks voltage-gated sodium channels