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Pharmacology · USMLE Step 1 · Healthcare and Nursing

USMLE Pharmacology: CNS Drugs

Anesthetics, antiepileptics, antidepressants, and antipsychotics with mechanism and one signature side effect per card.

About this set

45 mixed cards for USMLE Step 1 Pharmacology. Set 6 of 19 in USMLE Pharmacology. It opens with "What is the mechanism of action of nitrous oxide as a general anesthetic?" and "Nitrous oxide can cause ____ if 100% oxygen is not given at the end of". Study it alongside the other USMLE Step 1 sets below.

45 cards · mixed cards · AI-written, checked twice. Edit anything.

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What is the mechanism of action of nitrous oxide as a general anesthetic?
Show answerNMDA receptor antagonist
Nitrous oxide can cause ____ if 100% oxygen is not given at the end of anesthesia.
Show answerdiffusion hypoxia
What is the signature toxicity of halothane?
Show answerHepatotoxicity (halothane hepatitis)
Malignant hyperthermia is triggered by volatile anesthetics or succinylcholine in patients with a ____ gene mutation.
Show answerRYR1
What drug is used to treat malignant hyperthermia?
Show answerDantrolene
What is the mechanism of action of propofol?
Show answerPotentiates GABA-A receptor activity
What is a signature side effect of propofol?
Show answerHypotension from myocardial depression
What is the mechanism of action of ketamine?
Show answerNMDA receptor antagonist
What signature side effect is associated with ketamine?
Show answerEmergence delirium (hallucinations on awakening)
What is a signature side effect of etomidate?
Show answerAdrenocortical suppression
What is the mechanism of action of local anesthetics?
Show answerBlock voltage-gated sodium channels from the intracellular side
Ester-type local anesthetics are metabolized by plasma cholinesterase, while ____-type local anesthetics are metabolized by the liver.
Show answeramide
What is the mechanism of action of phenytoin?
Show answerBlocks voltage-gated sodium channels (use-dependent)
What signature side effect is associated with phenytoin?
Show answerGingival hyperplasia
What is the mechanism of action of carbamazepine?
Show answerBlocks voltage-gated sodium channels

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