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Pathology · USMLE Step 1

USMLE Pathology: Toxicology and Environmental Pathology

Heavy metal toxicity and environmental exposure organ pathology morphology, one finding per card.

33 cards · basic cards · AI-written, checked twice. Edit anything.

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Which RBC finding is classically seen in lead poisoning?
Basophilic stippling
What are the bluish gum line deposits seen in chronic lead poisoning called?
Burton lines
What is the classic childhood source of lead exposure?
Old lead-based paint chips
What renal histologic finding is seen in chronic lead nephropathy?
Intranuclear inclusion bodies in proximal tubule cells
What neuropsychiatric syndrome of irritability, mood lability, and tremor is caused by mercury toxicity?
Erethism
What is the classic dietary source of methylmercury exposure?
Contaminated fish, especially large predatory species
What condition with pink, peeling hands and feet occurs in children exposed to mercury?
Acrodynia (pink disease)
What breath odor is classic for acute arsenic poisoning?
Garlic odor
What nail finding is associated with arsenic poisoning?
Mees lines (transverse white lines)
What environmental source is classically linked to chronic arsenic poisoning?
Contaminated well water
What chronic skin change occurs with long term arsenic exposure?
Hyperkeratosis with hyperpigmentation
What disease of bone pain and fractures results from chronic cadmium exposure?
Itai-itai disease
Which part of the nephron is damaged by cadmium toxicity?
The proximal tubule
What toxic effect on hair is caused by thallium poisoning?
Alopecia (hair loss)
What skin color change is classic for carbon monoxide poisoning?
Cherry red skin discoloration

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