FlashKeepers

Pathology · USMLE Step 1

USMLE Pathology: Tumor Markers and Staging

Common serum tumor markers and TNM and grading staging systems used across organ systems, a cross-cutting oncology concept deck.

34 cards · basic cards · AI-written, checked twice. Edit anything.

Study this set free Look inside first Get FlashKeepers for iPhone
Which tumor marker is elevated in hepatocellular carcinoma?
Alpha-fetoprotein (AFP)
Which tumor marker is elevated in yolk sac (endodermal sinus) tumors?
Alpha-fetoprotein (AFP)
Which tumor marker is used to monitor for recurrence of colorectal carcinoma?
Carcinoembryonic antigen (CEA)
Which tumor marker is associated with ovarian cancer?
CA-125
Which tumor marker is associated with pancreatic adenocarcinoma?
CA 19-9
Which tumor marker is used for prostate cancer, though it is also elevated in benign prostatic hyperplasia and prostatitis?
Prostate-specific antigen (PSA)
Which tumor marker is characteristically elevated in choriocarcinoma?
Beta human chorionic gonadotropin (beta-hCG)
Besides choriocarcinoma, what other tumor type commonly elevates beta-hCG?
Testicular germ cell tumors
Which tumor marker is produced by parafollicular C cells and used to detect medullary thyroid carcinoma?
Calcitonin
Which serum marker is used to detect neuroendocrine tumors?
Chromogranin A
Which immunohistochemical marker is characteristic of melanoma?
S-100
Besides melanoma, what other condition stains positive for S-100?
Langerhans cell histiocytosis
Which enzyme marker, tartrate-resistant acid phosphatase, is used to diagnose a leukemia with 'hairy' cells?
Hairy cell leukemia
Which serum marker is elevated in osteosarcoma and Paget disease of bone?
Alkaline phosphatase
Which enzyme is used as a marker of tumor burden in seminoma and lymphoma rather than as a specific diagnostic marker?
Lactate dehydrogenase (LDH)

19 more cards in the app