Oral cavity, salivary gland, and laryngeal pathology morphology, distinct from the thyroid focus of the endocrine pathology deck.
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- What is an aphthous ulcer?
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A recurrent, painful, non-infectious oral mucosal ulcer (canker sore).
- Recurrent aphthous ulcers are classically associated with which two systemic diseases?
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Behcet disease and inflammatory bowel disease (Crohn disease).
- What organism causes oral candidiasis (thrush)?
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Candida albicans.
- How do you distinguish oral candidiasis from leukoplakia on exam?
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Candidiasis plaques scrape off; leukoplakia does not.
- Define oral leukoplakia.
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A white mucosal patch that cannot be scraped off and cannot be attributed to another diagnosis; it is a precancerous lesion.
- How does erythroplakia differ from leukoplakia in malignant potential?
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Erythroplakia (a red patch) carries a much higher risk of dysplasia or carcinoma than leukoplakia.
- What virus causes oral hairy leukoplakia?
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Epstein-Barr virus (EBV).
- Where on the oral mucosa does oral hairy leukoplakia classically appear?
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The lateral tongue.
- What is the most common malignancy of the oral cavity?
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Squamous cell carcinoma.
- What are the two major risk factors for oral squamous cell carcinoma?
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Tobacco use and alcohol use.
- What is actinic cheilitis?
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A precancerous lesion of the lip caused by chronic sun exposure.
- What virus reactivates to cause herpes labialis (cold sores)?
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Herpes simplex virus type 1 (HSV-1).
- What causes an oral mucocele?
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Rupture of a minor salivary gland duct, causing mucin to pool in the surrounding connective tissue.
- What is a ranula?
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A mucocele arising from the sublingual gland, presenting as a swelling on the floor of the mouth.
- What is a pyogenic granuloma of the gingiva sometimes called, given its association with pregnancy?
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A pregnancy tumor (granuloma gravidarum).