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Pathology · USMLE Step 1

USMLE Pathology: Head and Neck

Oral cavity, salivary gland, and laryngeal pathology morphology, distinct from the thyroid focus of the endocrine pathology deck.

34 cards · basic cards · AI-written, checked twice. Edit anything.

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What is an aphthous ulcer?
A recurrent, painful, non-infectious oral mucosal ulcer (canker sore).
Recurrent aphthous ulcers are classically associated with which two systemic diseases?
Behcet disease and inflammatory bowel disease (Crohn disease).
What organism causes oral candidiasis (thrush)?
Candida albicans.
How do you distinguish oral candidiasis from leukoplakia on exam?
Candidiasis plaques scrape off; leukoplakia does not.
Define oral leukoplakia.
A white mucosal patch that cannot be scraped off and cannot be attributed to another diagnosis; it is a precancerous lesion.
How does erythroplakia differ from leukoplakia in malignant potential?
Erythroplakia (a red patch) carries a much higher risk of dysplasia or carcinoma than leukoplakia.
What virus causes oral hairy leukoplakia?
Epstein-Barr virus (EBV).
Where on the oral mucosa does oral hairy leukoplakia classically appear?
The lateral tongue.
What is the most common malignancy of the oral cavity?
Squamous cell carcinoma.
What are the two major risk factors for oral squamous cell carcinoma?
Tobacco use and alcohol use.
What is actinic cheilitis?
A precancerous lesion of the lip caused by chronic sun exposure.
What virus reactivates to cause herpes labialis (cold sores)?
Herpes simplex virus type 1 (HSV-1).
What causes an oral mucocele?
Rupture of a minor salivary gland duct, causing mucin to pool in the surrounding connective tissue.
What is a ranula?
A mucocele arising from the sublingual gland, presenting as a swelling on the floor of the mouth.
What is a pyogenic granuloma of the gingiva sometimes called, given its association with pregnancy?
A pregnancy tumor (granuloma gravidarum).

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