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Pathology · USMLE Step 1 · Healthcare and Nursing

USMLE Pathology: Hematologic System

Bone marrow and peripheral smear morphology for anemias, leukemias, and lymphomas, distinct from the clinical-management focus of the Hematology and Oncology deck.

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39 basic cards for USMLE Step 1 Pathology. Set 9 of 27 in USMLE Pathology. It opens with "What is the classic peripheral smear finding in iron deficiency anemia?" and "What elongated RBC shape is seen in severe iron deficiency anemia?". Study it alongside the other USMLE Step 1 sets below.

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What is the classic peripheral smear finding in iron deficiency anemia?
Show answerMicrocytic, hypochromic RBCs
What elongated RBC shape is seen in severe iron deficiency anemia?
Show answerPencil cells (elliptocytes)
What neutrophil finding is characteristic of megaloblastic anemia?
Show answerHypersegmented neutrophils (6+ lobes)
What large, oval RBCs are seen in megaloblastic anemia?
Show answerMacro-ovalocytes
What special stain and finding confirms sideroblastic anemia?
Show answerRinged sideroblasts on Prussian blue (iron) stain
What RBC morphology is seen in hereditary spherocytosis?
Show answerSpherocytes (small, round cells lacking central pallor)
What RBC finding is characteristic of G6PD deficiency during a hemolytic episode?
Show answerBite cells
What denatured hemoglobin inclusion is seen in G6PD deficiency?
Show answerHeinz bodies
What RBC shape defines sickle cell anemia on smear?
Show answerSickle-shaped (crescent) RBCs
What nuclear remnant appears in RBCs after splenic dysfunction, as in sickle cell disease?
Show answerHowell-Jolly bodies
What RBC finding is seen in thalassemia?
Show answerTarget cells
What fragmented RBCs are seen in microangiopathic hemolytic anemia?
Show answerSchistocytes
What is the characteristic bone marrow finding in aplastic anemia?
Show answerHypocellular marrow with fatty replacement
What teardrop-shaped RBC is seen when marrow space is infiltrated by fibrosis or tumor?
Show answerDacrocyte (teardrop cell)
What RBC inclusion is characteristic of lead poisoning?
Show answerBasophilic stippling

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