Cell injury, inflammation, wound healing, and neoplasia vocabulary that underlies every organ-specific pathology topic, one concept per card.
39 cards · basic cards · AI-written, checked twice. Edit anything.
- What is the earliest reversible morphologic change in cell injury caused by ATP depletion?
Show answer
Cellular (hydropic) swelling- Which type of necrosis is typical of ischemic infarction in most organs except the brain?
Show answer
Coagulative necrosis- Which type of necrosis is characteristic of brain infarcts and bacterial abscesses?
Show answer
Liquefactive necrosis- What type of necrosis produces a cheese-like appearance and is classically seen in tuberculosis granulomas?
Show answer
Caseous necrosis- What type of necrosis occurs in acute pancreatitis when lipases break down peripancreatic fat?
Show answer
Fat necrosis- What process forms chalky white deposits during fat necrosis?
Show answer
Saponification, calcium binding to released fatty acids- What type of necrosis involves fibrin-like protein deposition in vessel walls and is seen in vasculitis or malignant hypertension?
Show answer
Fibrinoid necrosis- By what mechanism do free radicals damage cell membranes?
Show answer
Lipid peroxidation- What term describes additional cell damage caused by free radicals when blood flow is restored after ischemia?
Show answer
Reperfusion injury- Cyanide causes cell injury by inhibiting which mitochondrial enzyme complex?
Show answer
Cytochrome c oxidase (Complex IV)- What are the five cardinal signs of acute inflammation?
Show answer
Redness, heat, swelling, pain, and loss of function- Which leukocyte predominates in the first 24 to 48 hours of acute inflammation?
Show answer
Neutrophils- Which two cell types predominate in chronic inflammation?
Show answer
Macrophages and lymphocytes- What is the correct order of steps in leukocyte extravasation from blood vessels?
Show answer
Margination, rolling, adhesion, transmigration- Which adhesion molecules mediate the rolling of leukocytes along endothelium?
Show answer
Selectins
FlashKeepers