Breast pathology morphology including fibroadenoma, ductal carcinoma in situ, and invasive carcinoma subtypes, one finding per card.
About this set
32 basic cards for USMLE Step 1 Pathology. Set 1 of 27 in USMLE Pathology. It opens with "What is the most common benign breast tumor in women under 30?" and "On exam, a fibroadenoma classically feels like what kind of mass?". Study it alongside the other USMLE Step 1 sets below.
32 cards · basic cards · AI-written, checked twice. Edit anything.
- What is the most common benign breast tumor in women under 30?
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Fibroadenoma- On exam, a fibroadenoma classically feels like what kind of mass?
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A well-circumscribed, mobile, rubbery mass (sometimes called a breast mouse)- Phyllodes tumors typically occur in which age group, compared to fibroadenomas?
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Older women, typically in their 40s to 60s- What histologic pattern is characteristic of a phyllodes tumor?
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Leaf-like fronds with stromal overgrowth- Unlike fibroadenoma, a phyllodes tumor can behave in what way?
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It can be malignant- What is the classic presenting symptom of an intraductal papilloma?
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Bloody or serous nipple discharge- What is the histologic finding in intraductal papilloma?
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A papillary growth within a single dilated duct- What history is classically associated with fat necrosis of the breast?
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Trauma to the breast- Why is fat necrosis clinically important despite being benign?
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It can mimic carcinoma on exam and imaging- What is the histologic appearance of fat necrosis?
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Necrotic fat with lipid-laden macrophages and saponification- Fibrocystic change is the most common cause of a breast lump in which age group?
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Premenopausal women aged 20 to 40- Which subtype of fibrocystic change actually increases breast cancer risk?
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Atypical hyperplasia- What defines ductal carcinoma in situ (DCIS)?
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Malignant epithelial cells confined within the duct, with an intact basement membrane- Which DCIS subtype shows central necrosis and is linked to calcifications on mammography?
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Comedocarcinoma- What molecular change is the hallmark of lobular carcinoma in situ (LCIS)?
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Loss of E-cadherin expression
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