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Internal Medicine · USMLE Step 2 CK · Healthcare and Nursing

USMLE Step 2 CK Internal Medicine: Gastroenterology and Renal

Best next diagnostic or management step for adult GI, hepatic, and renal presentations tested on USMLE Step 2 CK.

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39 basic cards for USMLE Step 2 CK Internal Medicine. Set 4 of 7 in USMLE Step 2 CK Internal Medicine. It opens with "A patient has typical GERD symptoms (heartburn, regurgitation) with no alarm" and "A patient with dysphagia also has weight loss and is over 50 years old. What is". Study it alongside the other USMLE Step 2 CK sets below.

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A patient has typical GERD symptoms (heartburn, regurgitation) with no alarm features. What is the best initial management step?
Show answerEmpiric trial of a proton pump inhibitor
A patient with dysphagia also has weight loss and is over 50 years old. What is the next diagnostic step?
Show answerUpper endoscopy (EGD)
A barium esophagram shows a dilated esophagus with distal tapering ('bird's beak'). What diagnosis does this suggest?
Show answerAchalasia
After a barium esophagram suggests achalasia, what test confirms the diagnosis?
Show answerEsophageal manometry
Which single lab test is most useful for diagnosing acute pancreatitis?
Show answerSerum lipase
Diagnosing acute pancreatitis requires meeting 2 of which 3 criteria?
Show answerCharacteristic abdominal pain, lipase or amylase over 3 times the upper limit of normal, and characteristic imaging findings
What is the best initial imaging study for suspected acute cholecystitis?
Show answerRight upper quadrant ultrasound
RUQ ultrasound is equivocal for acute cholecystitis. What is the next best test?
Show answerHIDA scan (cholescintigraphy)
A patient has a dilated common bile duct and rising liver enzymes suggesting choledocholithiasis. What is the best next imaging step?
Show answerMRCP (magnetic resonance cholangiopancreatography)
A hemodynamically stable patient presents with an acute upper GI bleed. Within what timeframe should endoscopy be performed after resuscitation?
Show answerWithin 24 hours
A cirrhotic patient presents with suspected variceal hemorrhage. What medication should be started before endoscopy?
Show answerOctreotide
A hospitalized patient develops new watery diarrhea after antibiotic use. What is the best initial diagnostic test?
Show answerStool PCR or toxin assay for Clostridioides difficile
What is the best initial screening test for celiac disease?
Show answerTissue transglutaminase IgA antibody (tTG-IgA)
A patient has a positive tTG-IgA antibody test. What confirms the diagnosis of celiac disease?
Show answerDuodenal biopsy showing villous atrophy
A patient with suspected peptic ulcer disease needs testing for H. pylori without endoscopy. Which noninvasive tests are used?
Show answerUrea breath test or stool antigen test

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