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Pathology · USMLE Step 1 · Healthcare and Nursing

USMLE Neuropathology

CNS tumor types, neurodegenerative disease histology, and classic stroke and demyelination patterns, one finding per card. Original cards testing the underlying concepts.

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40 basic cards for USMLE Step 1 Pathology. It opens with "Which primary CNS tumor is the most common malignant brain tumor in adults?" and "What histologic hallmark is seen in glioblastoma?". Study it alongside the other USMLE Step 1 sets below.

40 cards · basic cards · AI-written, checked twice. Edit anything.

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Which primary CNS tumor is the most common malignant brain tumor in adults?
Show answerGlioblastoma (GBM)
What histologic hallmark is seen in glioblastoma?
Show answerPseudopalisading necrosis (tumor cells lined up around necrotic areas)
What gross growth pattern lets glioblastoma cross the corpus callosum?
Show answerIt grows across the midline, forming a butterfly glioma
From what cell type does a meningioma arise?
Show answerArachnoid cap cells
What concentric, calcified structures are seen histologically in meningioma?
Show answerPsammoma bodies
Is a meningioma an intra-axial or extra-axial tumor?
Show answerExtra-axial, attached to the dura
What immunohistochemical marker is positive in schwannoma?
Show answerS-100
Bilateral vestibular schwannomas are characteristic of which genetic syndrome?
Show answerNeurofibromatosis type 2
What classic histologic appearance describes oligodendroglioma cells?
Show answerFried egg appearance (round nuclei with clear halos)
What chromosomal deletion is characteristic of oligodendroglioma?
Show answerCodeletion of chromosome arms 1p and 19q
What eosinophilic fiber is seen histologically in pilocytic astrocytoma?
Show answerRosenthal fibers
What is the most common brain tumor of childhood?
Show answerPilocytic astrocytoma
What rosette pattern is characteristic of medulloblastoma?
Show answerHomer Wright rosettes
What histologic pattern is characteristic of ependymoma?
Show answerPerivascular pseudorosettes
From what embryologic structure does a craniopharyngioma arise?
Show answerRemnants of Rathke pouch

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