CNS tumor types, neurodegenerative disease histology, and classic stroke and demyelination patterns, one finding per card. Original cards testing the underlying concepts.
40 cards · basic cards · AI-written, checked twice. Edit anything.
- Which primary CNS tumor is the most common malignant brain tumor in adults?
- Glioblastoma (GBM)
- What histologic hallmark is seen in glioblastoma?
- Pseudopalisading necrosis (tumor cells lined up around necrotic areas)
- What gross growth pattern lets glioblastoma cross the corpus callosum?
- It grows across the midline, forming a butterfly glioma
- From what cell type does a meningioma arise?
- Arachnoid cap cells
- What concentric, calcified structures are seen histologically in meningioma?
- Psammoma bodies
- Is a meningioma an intra-axial or extra-axial tumor?
- Extra-axial, attached to the dura
- What immunohistochemical marker is positive in schwannoma?
- S-100
- Bilateral vestibular schwannomas are characteristic of which genetic syndrome?
- Neurofibromatosis type 2
- What classic histologic appearance describes oligodendroglioma cells?
- Fried egg appearance (round nuclei with clear halos)
- What chromosomal deletion is characteristic of oligodendroglioma?
- Codeletion of chromosome arms 1p and 19q
- What eosinophilic fiber is seen histologically in pilocytic astrocytoma?
- Rosenthal fibers
- What is the most common brain tumor of childhood?
- Pilocytic astrocytoma
- What rosette pattern is characteristic of medulloblastoma?
- Homer Wright rosettes
- What histologic pattern is characteristic of ependymoma?
- Perivascular pseudorosettes
- From what embryologic structure does a craniopharyngioma arise?
- Remnants of Rathke pouch