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Microbiology · USMLE Step 1 · Healthcare and Nursing

USMLE Microbiology: Bugs and Diseases II

Fungi, parasites, and remaining high-yield bugs matched to the disease they cause and one distinguishing feature.

About this set

48 basic cards for USMLE Step 1 Microbiology. Set 5 of 12 in USMLE Microbiology. It opens with "Candida albicans" and "Aspergillus fumigatus". Study it alongside the other USMLE Step 1 sets below.

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Candida albicans
Show answerOral/vaginal thrush, esophageal infection; pseudohyphae with budding (gram-positive)
Aspergillus fumigatus
Show answerAspergillosis (respiratory infections, invasive); septate hyphae with acute-angle branching
Cryptococcus neoformans
Show answerCryptococcal meningitis, respiratory infection; polysaccharide capsule visible on India ink stain
Histoplasma capsulatum
Show answerHistoplasmosis (respiratory); endemic to Ohio and Mississippi river valleys
Blastomyces dermatitidis
Show answerBlastomycosis (respiratory, skin); endemic North America, broad-based budding yeast
Coccidioides immitis
Show answerCoccidioidomycosis (Valley Fever); endemic to southwestern US, spherule with endospores
Pneumocystis jirovecii
Show answerPCP (pneumonia in immunocompromised, especially AIDS CD4 < 200); visible on silver or GMS stain
Mucor and Rhizopus species
Show answerMucormycosis (angioinvasive, rapid progression); non-septate hyphae with right-angle branching
Candida auris
Show answerInvasive candidiasis, multidrug resistance; emerging pathogen, poorly susceptible to azoles
Plasmodium falciparum
Show answerMalaria (falciparum type); highest mortality, risk of cerebral malaria and hemolysis
Plasmodium vivax
Show answerMalaria (vivax type); relapsing fever, hypnozoites in liver enable relapses
Trypanosoma brucei
Show answerAfrican sleeping sickness; flagellated protozoan, crosses blood-brain barrier causing CNS disease
Trypanosoma cruzi
Show answerChagas disease; C-shaped trypanosome, reduviid bug vector (kissing bug), cardiac involvement
Leishmania donovani
Show answerVisceral leishmaniasis (kala azar); intracellular amastigote, spleen/liver enlargement
Toxoplasma gondii
Show answerToxoplasmosis; cat reservoir (definitive host), bradyzoites in tissue cysts, CNS/eye involvement

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