Causative organisms of common sexually transmitted infections matched to their hallmark presentation and lab identification tested on USMLE Step 1.
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- What is the Gram stain morphology of Neisseria gonorrhoeae?
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Gram-negative diplococci
- Which selective agar is used to culture Neisseria gonorrhoeae?
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Thayer-Martin agar
- What is the classic presentation of gonococcal urethritis?
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Purulent urethral discharge
- What is the triad of disseminated gonococcal infection?
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Migratory polyarthritis, dermatitis (pustular skin lesions), and tenosynovitis
- Chlamydia trachomatis serovars D through K cause which condition?
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Urethritis and cervicitis
- Chlamydia trachomatis serovars L1 to L3 cause which disease?
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Lymphogranuloma venereum
- Why can Chlamydia trachomatis not be visualized by Gram stain?
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It is an obligate intracellular organism that lacks a peptidoglycan cell wall
- What stain is used to detect chlamydial intracellular inclusion bodies?
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Giemsa stain
- A painless genital ulcer (chancre) is the hallmark of which stage of syphilis?
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Primary syphilis
- A diffuse rash involving the palms and soles is characteristic of which stage of syphilis?
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Secondary syphilis
- Granulomatous lesions called gummas occur in which stage of syphilis?
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Tertiary syphilis
- A pupil that accommodates but does not react to light is called what, and in which infection is it seen?
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Argyll Robertson pupil, seen in neurosyphilis
- What technique is used to directly visualize Treponema pallidum?
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Dark-field microscopy
- Name the two nontreponemal screening tests for syphilis.
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VDRL and RPR
- What is the confirmatory treponemal antibody test for syphilis?
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FTA-ABS