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Microbiology · USMLE Step 1 · Healthcare and Nursing

USMLE Microbiology: Viruses Classification

Virus families grouped by genome type and structure, with the key identifying feature and a representative disease for each.

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40 basic cards for USMLE Step 1 Microbiology. Set 12 of 12 in USMLE Microbiology. It opens with "What type of genome does Parvoviridae have?" and "Parvovirus B19 causes which classic childhood illness?". Study it alongside the other USMLE Step 1 sets below.

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What type of genome does Parvoviridae have?
Show answerSingle-stranded DNA (ssDNA)
Parvovirus B19 causes which classic childhood illness?
Show answerErythema infectiosum (fifth disease)
What is the genome/capsid structure of Papillomaviridae?
Show answerCircular double-stranded DNA, non-enveloped
High-risk HPV types (16, 18) are strongly associated with which cancer?
Show answerCervical cancer
What is the genome/capsid structure of Polyomaviridae?
Show answerCircular double-stranded DNA, non-enveloped
JC virus (Polyomaviridae) causes which demyelinating disease in immunosuppressed patients?
Show answerProgressive multifocal leukoencephalopathy (PML)
What is the genome/capsid structure of Adenoviridae?
Show answerLinear double-stranded DNA, non-enveloped, icosahedral capsid
Adenovirus classically causes which combination of symptoms?
Show answerPharyngoconjunctival fever (sore throat plus conjunctivitis)
What genome/envelope structure do all Herpesviridae share?
Show answerLinear double-stranded DNA, enveloped
Which herpesvirus is the classic cause of infectious mononucleosis?
Show answerEpstein-Barr virus (EBV)
Poxviridae is the only DNA virus family that replicates entirely in the ____ of the host cell.
Show answercytoplasm
Among all viruses that infect humans, Poxviridae holds which size distinction?
Show answerLargest human virus
What is the genome structure of Hepadnaviridae?
Show answerPartially double-stranded, circular DNA, enveloped
Hepatitis B virus (Hepadnaviridae) uniquely relies on which enzyme to replicate its DNA genome?
Show answerReverse transcriptase
What is the genome/capsid structure of Picornaviridae?
Show answerPositive-sense single-stranded RNA, non-enveloped, small icosahedral capsid

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