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Microbiology · USMLE Step 2 CK · Healthcare and Nursing

USMLE Step 2 CK Infectious Disease

Empiric antibiotic selection and infectious disease management scenarios tested on USMLE Step 2 CK.

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40 mixed cards for USMLE Step 2 CK Microbiology. It opens with "What is the first-line empiric antibiotic for a healthy outpatient with" and "Empiric antibiotic regimen for outpatient CAP in a patient with comorbidities". Study it alongside the other USMLE Step 2 CK sets below.

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What is the first-line empiric antibiotic for a healthy outpatient with community-acquired pneumonia and no comorbidities?
Show answerAmoxicillin
Empiric antibiotic regimen for outpatient CAP in a patient with comorbidities (heart, lung, liver, or renal disease, diabetes, or alcoholism)?
Show answerAmoxicillin-clavulanate plus a macrolide (or a respiratory fluoroquinolone alone)
Empiric antibiotic regimen for a patient hospitalized with CAP on a general medical floor (non-ICU)?
Show answerA beta-lactam plus a macrolide
Empiric antibiotic regimen for a patient with CAP admitted to the ICU?
Show answerA beta-lactam plus either azithromycin or a respiratory fluoroquinolone
Compared to community-acquired pneumonia, empiric therapy for hospital-acquired or ventilator-associated pneumonia must also cover ____.
Show answerPseudomonas aeruginosa
First-line oral antibiotic for uncomplicated acute cystitis in a nonpregnant woman?
Show answerNitrofurantoin
First-line empiric antibiotic for outpatient treatment of acute pyelonephritis?
Show answerAn oral fluoroquinolone (e.g., ciprofloxacin)
First-line empiric antibiotic for a patient hospitalized with severe pyelonephritis?
Show answerIV ceftriaxone
In a previously healthy adult under age 50 with suspected bacterial meningitis, empiric therapy is ____.
Show answervancomycin plus ceftriaxone
What antibiotic is added to the standard meningitis regimen in patients over age 50?
Show answerAmpicillin, to cover Listeria monocytogenes
Empiric antibiotic regimen for suspected bacterial meningitis in a neonate?
Show answerAmpicillin plus cefotaxime
When should dexamethasone be given relative to antibiotics in suspected bacterial meningitis?
Show answerJust before or together with the first dose of antibiotics
Empiric antibiotic regimen for suspected septic (bacterial) arthritis before culture results return?
Show answerVancomycin plus ceftriaxone
Empiric antibiotic regimen for necrotizing fasciitis?
Show answerVancomycin plus piperacillin-tazobactam plus clindamycin
Why is clindamycin included in the treatment regimen for necrotizing fasciitis and toxic shock syndrome?
Show answerIt suppresses bacterial exotoxin production

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