Microbiology · USMLE Step 1

USMLE Microbiology: Fungi and Parasites Classification

Fungal and parasitic organisms grouped by class and transmission route, with the key lab or clinical identifying feature for each.

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Which dimorphic fungus is endemic to the Ohio and Mississippi River valleys and associated with bird or bat droppings?
Histoplasma capsulatum
Which dimorphic fungus appears as a broad-based budding yeast in tissue and is found in soil?
Blastomyces dermatitidis
Which dimorphic fungus forms spherules packed with endospores in infected tissue?
Coccidioides immitis
Which dimorphic fungus produces yeast cells budding in a 'captain's wheel' pattern?
Paracoccidioides brasiliensis
Which dimorphic fungus causes 'rose gardener's disease' after a thorn prick or traumatic inoculation?
Sporothrix schenckii
Which three fungal genera cause tinea (ringworm) infections of skin, hair, and nails?
Microsporum, Trichophyton, and Epidermophyton
What microscopic finding on a KOH skin scraping confirms a dermatophyte infection?
Branching septate hyphae
Which fungus causes tinea versicolor and shows a 'spaghetti and meatballs' pattern on KOH prep?
Malassezia furfur
What lab test identifies Candida albicans by its growth of germ tubes in serum at 37 C?
Germ tube test
What hyphal branching pattern is characteristic of Aspergillus fumigatus?
Septate hyphae branching at acute (45-degree) angles
What hyphal branching pattern is characteristic of Mucor and Rhizopus?
Broad, nonseptate hyphae branching at wide (90-degree) angles
What stain demonstrates the polysaccharide capsule of Cryptococcus neoformans?
India ink stain
Which fungus causes diffuse interstitial pneumonia in AIDS patients with a CD4 count below 200?
Pneumocystis jirovecii
Which protozoan causes fecal-oral diarrhea and has a trophozoite with two nuclei resembling 'owl eyes'?
Giardia lamblia
Which protozoan causes flask-shaped colonic ulcers and liver abscesses with anchovy paste exudate?
Entamoeba histolytica

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