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Cardiology · USMLE Step 1 · Healthcare and Nursing

USMLE Cardiology: Valvular Heart Disease

Valvular heart disease pathophysiology and hemodynamic consequences tested on USMLE Step 1, deeper than the auscultation focus of the murmurs and heart sounds deck.

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35 basic cards for USMLE Step 1 Cardiology. Set 4 of 4 in USMLE Cardiology. It opens with "In patients over 65, what is the most common cause of aortic stenosis?" and "In patients under 65, what is the most common cause of aortic stenosis?". Study it alongside the other USMLE Step 1 sets below.

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In patients over 65, what is the most common cause of aortic stenosis?
Show answerCalcific (degenerative) aortic valve disease
In patients under 65, what is the most common cause of aortic stenosis?
Show answerBicuspid aortic valve
What type of left ventricular hypertrophy results from the chronic pressure overload of aortic stenosis?
Show answerConcentric hypertrophy
What carotid pulse finding is classic for severe aortic stenosis?
Show answerPulsus parvus et tardus (weak and delayed upstroke)
The classic symptom triad of severe aortic stenosis is angina, ____, and heart failure.
Show answersyncope
Why does severe aortic stenosis cause exertional syncope?
Show answerFixed cardiac output cannot rise to match exercise-induced peripheral vasodilation, causing cerebral hypoperfusion
Why does severe aortic stenosis cause angina even without coronary artery disease?
Show answerLV hypertrophy raises myocardial oxygen demand while high intraventricular pressure lowers coronary perfusion pressure
Roughly what is the average survival after a patient with aortic stenosis develops heart failure symptoms, without valve replacement?
Show answerAbout 2 years
What type of left ventricular change results from the chronic volume overload of aortic regurgitation?
Show answerEccentric hypertrophy (ventricular dilation)
What is the rapidly rising and suddenly collapsing pulse of severe aortic regurgitation called?
Show answerCorrigan pulse (water-hammer pulse)
What is the head-bobbing sign seen with each heartbeat in severe aortic regurgitation called?
Show answerde Musset sign
Besides bicuspid aortic valve, what connective tissue disorder causing aortic root dilation can lead to aortic regurgitation?
Show answerMarfan syndrome
Why is acute aortic regurgitation poorly tolerated compared to chronic aortic regurgitation?
Show answerThe LV has no time to dilate and compensate, so LV diastolic pressure rises rapidly, causing pulmonary edema and cardiogenic shock
What is the most common cause of mitral stenosis worldwide?
Show answerRheumatic heart disease
How does mitral stenosis predispose to atrial fibrillation?
Show answerElevated left atrial pressure causes left atrial enlargement, which promotes atrial fibrillation

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