Valvular heart disease pathophysiology and hemodynamic consequences tested on USMLE Step 1, deeper than the auscultation focus of the murmurs and heart sounds deck.
About this set
35 basic cards for USMLE Step 1 Cardiology. Set 4 of 4 in USMLE Cardiology. It opens with "In patients over 65, what is the most common cause of aortic stenosis?" and "In patients under 65, what is the most common cause of aortic stenosis?". Study it alongside the other USMLE Step 1 sets below.
35 cards · basic cards · AI-written, checked twice. Edit anything.
- In patients over 65, what is the most common cause of aortic stenosis?
Show answer
Calcific (degenerative) aortic valve disease
- In patients under 65, what is the most common cause of aortic stenosis?
Show answer
Bicuspid aortic valve
- What type of left ventricular hypertrophy results from the chronic pressure overload of aortic stenosis?
Show answer
Concentric hypertrophy
- What carotid pulse finding is classic for severe aortic stenosis?
Show answer
Pulsus parvus et tardus (weak and delayed upstroke)
- The classic symptom triad of severe aortic stenosis is angina, ____, and heart failure.
Show answer
syncope
- Why does severe aortic stenosis cause exertional syncope?
Show answer
Fixed cardiac output cannot rise to match exercise-induced peripheral vasodilation, causing cerebral hypoperfusion
- Why does severe aortic stenosis cause angina even without coronary artery disease?
Show answer
LV hypertrophy raises myocardial oxygen demand while high intraventricular pressure lowers coronary perfusion pressure
- Roughly what is the average survival after a patient with aortic stenosis develops heart failure symptoms, without valve replacement?
Show answer
About 2 years
- What type of left ventricular change results from the chronic volume overload of aortic regurgitation?
Show answer
Eccentric hypertrophy (ventricular dilation)
- What is the rapidly rising and suddenly collapsing pulse of severe aortic regurgitation called?
Show answer
Corrigan pulse (water-hammer pulse)
- What is the head-bobbing sign seen with each heartbeat in severe aortic regurgitation called?
Show answer
de Musset sign
- Besides bicuspid aortic valve, what connective tissue disorder causing aortic root dilation can lead to aortic regurgitation?
Show answer
Marfan syndrome
- Why is acute aortic regurgitation poorly tolerated compared to chronic aortic regurgitation?
Show answer
The LV has no time to dilate and compensate, so LV diastolic pressure rises rapidly, causing pulmonary edema and cardiogenic shock
- What is the most common cause of mitral stenosis worldwide?
Show answer
Rheumatic heart disease
- How does mitral stenosis predispose to atrial fibrillation?
Show answer
Elevated left atrial pressure causes left atrial enlargement, which promotes atrial fibrillation