Internal Medicine · USMLE Step 2 CK

USMLE Step 2 CK Internal Medicine

Common adult inpatient and outpatient presentations with the best next diagnostic or management step, as tested on USMLE Step 2 CK.

49 cards · basic cards · AI-written, checked twice. Edit anything.

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What is the next step in management for a patient with ST-elevation on ECG and ongoing chest pain?
Emergent reperfusion with percutaneous coronary intervention (PCI)
Best initial imaging test for a hemodynamically stable patient with suspected pulmonary embolism?
CT pulmonary angiography
Preferred imaging for suspected PE when a patient has severe renal impairment or contrast allergy?
Ventilation-perfusion (V/Q) scan
First-line outpatient antibiotic for a healthy adult with community-acquired pneumonia and no comorbidities?
Amoxicillin (or a macrolide)
Empiric antibiotic regimen for a hospitalized non-ICU patient with community-acquired pneumonia?
A beta-lactam plus a macrolide
Acute pancreatitis is diagnosed when at least ____ criteria are met: characteristic abdominal pain, lipase/amylase over 3 times normal, or imaging findings of pancreatitis.
2 of 3
Most useful initial lab test when acute pancreatitis is suspected?
Serum lipase
First-line imaging study for suspected acute cholecystitis?
Right upper quadrant ultrasound
Best next step when choledocholithiasis is suspected after ultrasound shows a dilated common bile duct but no clear stone?
MRCP (magnetic resonance cholangiopancreatography)
Within what time frame should upper endoscopy be performed in a hemodynamically stable patient with an upper GI bleed?
Within 24 hours
What drug class is used for primary prophylaxis against variceal hemorrhage in cirrhotic patients with medium or large varices?
Nonselective beta blockers
Preferred test to diagnose Clostridioides difficile infection in a symptomatic patient?
Stool PCR or toxin assay for C. difficile
First-line treatment for an initial episode of C. difficile colitis?
Oral vancomycin or fidaxomicin
Initial management for a hemodynamically stable patient with new-onset atrial fibrillation and rapid ventricular rate?
Rate control with a beta blocker or nondihydropyridine calcium channel blocker
Management of atrial fibrillation in a patient who is hemodynamically unstable?
Immediate synchronized electrical cardioversion

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