Common adult inpatient and outpatient presentations with the best next diagnostic or management step, as tested on USMLE Step 2 CK.
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- What is the next step in management for a patient with ST-elevation on ECG and ongoing chest pain?
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Emergent reperfusion with percutaneous coronary intervention (PCI)
- Best initial imaging test for a hemodynamically stable patient with suspected pulmonary embolism?
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CT pulmonary angiography
- Preferred imaging for suspected PE when a patient has severe renal impairment or contrast allergy?
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Ventilation-perfusion (V/Q) scan
- First-line outpatient antibiotic for a healthy adult with community-acquired pneumonia and no comorbidities?
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Amoxicillin (or a macrolide)
- Empiric antibiotic regimen for a hospitalized non-ICU patient with community-acquired pneumonia?
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A beta-lactam plus a macrolide
- Acute pancreatitis is diagnosed when at least ____ criteria are met: characteristic abdominal pain, lipase/amylase over 3 times normal, or imaging findings of pancreatitis.
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2 of 3
- Most useful initial lab test when acute pancreatitis is suspected?
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Serum lipase
- First-line imaging study for suspected acute cholecystitis?
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Right upper quadrant ultrasound
- Best next step when choledocholithiasis is suspected after ultrasound shows a dilated common bile duct but no clear stone?
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MRCP (magnetic resonance cholangiopancreatography)
- Within what time frame should upper endoscopy be performed in a hemodynamically stable patient with an upper GI bleed?
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Within 24 hours
- What drug class is used for primary prophylaxis against variceal hemorrhage in cirrhotic patients with medium or large varices?
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Nonselective beta blockers
- Preferred test to diagnose Clostridioides difficile infection in a symptomatic patient?
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Stool PCR or toxin assay for C. difficile
- First-line treatment for an initial episode of C. difficile colitis?
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Oral vancomycin or fidaxomicin
- Initial management for a hemodynamically stable patient with new-onset atrial fibrillation and rapid ventricular rate?
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Rate control with a beta blocker or nondihydropyridine calcium channel blocker
- Management of atrial fibrillation in a patient who is hemodynamically unstable?
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Immediate synchronized electrical cardioversion