Internal Medicine · USMLE Step 2 CK

USMLE Step 2 CK Internal Medicine: Cardiology and Pulmonology

Best next diagnostic or management step for adult cardiac and pulmonary presentations tested on USMLE Step 2 CK, narrower than the general internal medicine deck.

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Suspected STEMI on ECG, what is the best next step in management?
Emergent reperfusion via primary PCI (door to balloon under 90 minutes)
Chest pain with a non-diagnostic initial ECG and suspected ACS, what is the next best step?
Serial troponins and repeat ECG
Stable patient with new exertional chest pain and a normal resting ECG, what is the best next diagnostic test?
Exercise or pharmacologic stress test
NSTEMI management, what combination of therapies is started immediately?
Dual antiplatelet therapy plus anticoagulation
Patient with suspected acute pericarditis, what is the best next test to check for a complicating effusion?
Transthoracic echocardiogram
Tearing chest pain radiating to the back with unequal blood pressures in both arms, what is the best next diagnostic step?
CT angiography of the chest
Hemodynamically unstable patient with suspected aortic dissection who cannot be moved to CT, what imaging is used instead?
Transesophageal echocardiogram
Fever with a new heart murmur and suspected infective endocarditis, what is the best next step before starting antibiotics?
Draw three sets of blood cultures from different sites
New onset atrial fibrillation in a hemodynamically stable patient, what is the initial management priority?
Rate control
In atrial fibrillation, what score is used to decide on anticoagulation?
CHA2DS2-VASc score
Atrial fibrillation with hypotension and altered mental status, what is the immediate next step?
Synchronized electrical cardioversion
Pulseless ventricular tachycardia, what is the immediate next step?
Unsynchronized defibrillation
Young athlete with exertional syncope and a systolic murmur that increases with Valsalva, what is the best next diagnostic test?
Echocardiogram
Patient with symptoms of heart failure, what is the best initial test to assess ejection fraction?
Transthoracic echocardiogram
New holosystolic murmur several days after a myocardial infarction, what is the best next step?
Echocardiogram to evaluate for papillary muscle rupture or ventricular septal defect

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