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Internal Medicine · USMLE Step 2 CK

USMLE Step 2 CK Outpatient Infectious Disease and Immunizations

Outpatient management of common infections and adult immunization schedules as tested on USMLE Step 2 CK.

39 cards · basic cards · AI-written, checked twice. Edit anything.

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What is the first-line oral antibiotic for uncomplicated cystitis in a nonpregnant woman?
Nitrofurantoin
How many days of nitrofurantoin are typically prescribed for uncomplicated cystitis?
5 days
What is an alternative first-line agent to nitrofurantoin for uncomplicated cystitis?
Trimethoprim-sulfamethoxazole (TMP-SMX)
What class of antibiotics is preferred for outpatient treatment of acute uncomplicated pyelonephritis?
Fluoroquinolones (e.g., ciprofloxacin)
In a healthy outpatient with no comorbidities, what are the first-line oral antibiotics for community-acquired pneumonia?
Amoxicillin, a macrolide (azithromycin), or doxycycline
In an outpatient with comorbidities such as diabetes or COPD, what antibiotic regimen is preferred for community-acquired pneumonia?
A respiratory fluoroquinolone, or a beta-lactam plus a macrolide
The CURB-65 score includes Confusion, Urea, Respiratory rate, Blood pressure, and age ____ or older to help decide if a pneumonia patient needs hospitalization.
65
What is the first-line antibiotic for streptococcal pharyngitis in a patient without a penicillin allergy?
Penicillin V (or amoxicillin)
What test is typically used to confirm strep pharyngitis before starting antibiotics?
Rapid antigen detection test
Name the four Centor criteria used to estimate the probability of strep pharyngitis.
Fever, tonsillar exudates, tender anterior cervical lymphadenopathy, and absence of cough
What is the first-line antibiotic for acute otitis media in children?
High-dose amoxicillin
What is the first-line antibiotic for acute bacterial rhinosinusitis?
Amoxicillin-clavulanate
After how many days of persistent, non-improving symptoms is acute rhinosinusitis considered likely bacterial rather than viral?
10 days
What is the first-line oral antibiotic for outpatient nonpurulent cellulitis?
Cephalexin
What antibiotics should be used for outpatient purulent cellulitis where MRSA is suspected?
Trimethoprim-sulfamethoxazole or doxycycline

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