Loop, thiazide, potassium-sparing, and osmotic diuretics with mechanism of action and one signature side effect per card.
37 cards · mixed cards · AI-written, checked twice. Edit anything.
- What is the mechanism of action of loop diuretics?
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They inhibit the Na-K-2Cl cotransporter.- In which part of the nephron do loop diuretics act?
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The thick ascending limb of the loop of Henle- What is the signature side effect of loop diuretics involving hearing?
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Ototoxicity- Name three loop diuretic drugs.
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Furosemide, bumetanide, and torsemide- Which loop diuretic lacks a sulfa moiety and can be used in patients with sulfa allergy?
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Ethacrynic acid- How do loop diuretics affect urinary calcium excretion?
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They increase calcium excretion, risking hypocalcemia- What potassium disturbance do loop diuretics cause?
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Hypokalemia- Why can loop diuretics precipitate gout attacks?
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They cause hyperuricemia by competing with uric acid for tubular secretion- What is a major clinical use of loop diuretics in acute heart failure?
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Treating pulmonary edema- Loop diuretics are used to treat which acute electrolyte emergency of excess serum calcium?
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Hypercalcemia- Furosemide
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Loop diuretic- What is the mechanism of action of thiazide diuretics?
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They inhibit the Na-Cl symporter- In which part of the nephron do thiazide diuretics act?
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The distal convoluted tubule- How do thiazide diuretics affect urinary calcium excretion?
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They decrease calcium excretion, causing hypercalcemia- What is the first-line diuretic class for treating essential hypertension in many patients?
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Thiazide diuretics
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