Classic toxidromes (anticholinergic, cholinergic, opioid, sympathomimetic) with their symptom pattern, one toxidrome per card.
39 cards · basic cards · AI-written, checked twice. Edit anything.
- What receptor type is blocked in anticholinergic toxidrome?
- Muscarinic acetylcholine receptors
- What happens to the pupils in anticholinergic toxidrome?
- Mydriasis (dilated pupils)
- Describe the skin findings in anticholinergic toxidrome.
- Dry, flushed, and hot skin from decreased sweating
- What happens to body temperature in anticholinergic toxidrome?
- Hyperthermia
- What urinary symptom is classic in anticholinergic toxidrome?
- Urinary retention
- What happens to bowel sounds in anticholinergic toxidrome?
- Decreased or absent bowel sounds (ileus)
- What CNS symptoms occur in anticholinergic toxidrome?
- Delirium, agitation, and visual hallucinations
- What happens to heart rate in anticholinergic toxidrome?
- Tachycardia
- Name a classic drug class that causes anticholinergic toxidrome.
- Antihistamines, such as diphenhydramine
- What is the antidote used for severe anticholinergic toxidrome?
- Physostigmine
- What is the underlying mechanism of cholinergic toxidrome?
- Acetylcholinesterase inhibition causing excess acetylcholine, seen with organophosphates and carbamates
- What happens to the pupils in cholinergic toxidrome?
- Miosis (pinpoint pupils)
- What does the mnemonic SLUDGE stand for in cholinergic toxidrome?
- Salivation, lacrimation, urination, defecation, GI distress, emesis
- What do the 'killer B's' refer to in cholinergic toxidrome?
- Bradycardia, bronchorrhea, and bronchospasm
- What nicotinic effects occur in cholinergic toxidrome?
- Muscle fasciculations and weakness