Antiemetics, proton pump inhibitors, and laxatives with their key nursing considerations and administration timing.
34 cards · basic cards · AI-written, checked twice. Edit anything.
- What drug class is ondansetron?
- A 5-HT3 receptor antagonist
- Why should a baseline ECG be considered before giving ondansetron to at-risk patients?
- Ondansetron can cause QT interval prolongation
- When is ondansetron typically given relative to chemotherapy?
- About 30 minutes before chemotherapy starts
- What drug class is promethazine?
- A phenothiazine antihistamine antiemetic
- What serious complication can occur if IV promethazine infiltrates or extravasates?
- Severe tissue damage or necrosis
- How should IV promethazine be given to reduce the risk of injection site injury?
- Diluted and given slowly into a large, well-functioning vein
- What is the mechanism of action of metoclopramide?
- Dopamine antagonist that increases GI motility and gastric emptying
- Metoclopramide carries a black box warning for ____ with prolonged use.
- tardive dyskinesia
- How long should metoclopramide use generally be limited to, per its black box warning?
- No longer than 12 weeks
- How far in advance should a scopolamine patch be applied before travel or surgery?
- At least 4 hours before the effect is needed
- Where on the body is a scopolamine transdermal patch applied?
- Behind the ear
- What activity precaution applies to most antiemetics due to drowsiness?
- Avoid driving or hazardous activities until the drug's effects are known
- What drug class do omeprazole and esomeprazole belong to?
- Proton pump inhibitor (PPI)
- What is the mechanism of action of proton pump inhibitors?
- They irreversibly block the H+/K+ ATPase pump in gastric parietal cells, reducing acid secretion
- When should a PPI ideally be taken relative to meals?
- 30 to 60 minutes before the first meal of the day