Antidepressants, antipsychotics, and mood stabilizers with their black box warnings and key nursing monitoring points.
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- What is the black box warning for SSRIs regarding suicidality?
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Increased risk of suicidal thinking and behavior in children, adolescents, and young adults up to age 24.- How long does it typically take for SSRIs to reach full therapeutic effect?
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4 to 6 weeks- What combination commonly triggers serotonin syndrome?
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An SSRI taken with an MAOI (or another serotonergic drug)- Serotonin syndrome presents with hyperthermia, agitation, tremor, and ____.
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hyperreflexia- What dietary restriction is required for patients taking MAOIs?
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Avoid tyramine-rich foods (aged cheese, cured meats, red wine)- What happens if a patient on an MAOI eats tyramine-rich food?
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Hypertensive crisis- How long should a patient wait after stopping fluoxetine before starting an MAOI?
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About 5 weeks, due to fluoxetine's long half-life- Why are tricyclic antidepressant (TCA) overdoses especially dangerous?
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They are cardiotoxic and can cause fatal arrhythmias- Do TCAs carry the same suicidality black box warning as SSRIs?
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Yes, increased suicidality risk in children, adolescents, and young adults- What two conditions are contraindications for bupropion?
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Seizure disorder and eating disorder- What vital sign should be monitored closely with venlafaxine, an SNRI?
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Blood pressure, for risk of hypertension- What is the therapeutic serum range for lithium?
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0.6 to 1.2 mEq/L- What are early signs of lithium toxicity?
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Nausea, vomiting, diarrhea, and fine tremor- What are signs of severe, late-stage lithium toxicity?
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Ataxia, confusion, seizures, and cardiac arrhythmias- How does low sodium intake affect lithium levels?
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It increases the risk of lithium toxicity
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