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Nursing Pharmacology · NCLEX-RN

Nursing Pharmacology: High-Alert Medications and Safety

ISMP high-alert medication categories and the double-check and safety protocols nurses use to administer them.

30 cards · basic cards · AI-written, checked twice. Edit anything.

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What organization publishes the official U.S. list of high-alert medications?
The Institute for Safe Medication Practices (ISMP)
High-alert medications are not necessarily involved in ____ than other drugs, but errors with them are more likely to cause serious harm.
more errors
What is the defining feature of a high-alert medication?
It carries a heightened risk of causing significant patient harm if used in error
Which high-alert drug class includes heparin and warfarin?
Anticoagulants (antithrombotic agents)
Why is insulin classified as a high-alert medication?
Dosing errors or mix-ups between insulin types can cause severe, rapid hypoglycemia
Why are neuromuscular blocking agents classified as high-alert?
They cause respiratory paralysis and can be fatal without ventilatory support
What must be in place before giving a neuromuscular blocking agent?
A secured airway with ventilatory support
Where should concentrated potassium chloride vials generally not be stored?
In patient care unit floor stock
What is an independent double-check?
A second qualified clinician separately verifies the drug, dose, and pump settings before administration
During an independent double-check, should the second nurse see the first nurse's calculation before checking?
No, the second nurse should calculate independently first
Name the three things typically verified during an independent double-check of an IV opioid infusion.
The drug, the concentration/dose, and the pump rate/programming
What lab value monitors the therapeutic effect of unfractionated heparin?
aPTT (activated partial thromboplastin time)
What lab value monitors warfarin therapy?
INR (international normalized ratio)
What is the antidote for heparin overdose?
Protamine sulfate
What is the antidote for warfarin overdose?
Vitamin K (phytonadione)

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