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Nursing Pharmacology · NCLEX-RN · Healthcare and Nursing

Nursing Pharmacology: High-Alert Medications and Safety

ISMP high-alert medication categories and the double-check and safety protocols nurses use to administer them.

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30 basic cards for NCLEX-RN Nursing Pharmacology. Set 12 of 21 in Nursing Pharmacology. It opens with "What organization publishes the official U.S. list of high-alert medications?" and "High-alert medications are not necessarily involved in ____ than other drugs". Study it alongside the other NCLEX-RN sets below.

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What organization publishes the official U.S. list of high-alert medications?
Show answerThe Institute for Safe Medication Practices (ISMP)
High-alert medications are not necessarily involved in ____ than other drugs, but errors with them are more likely to cause serious harm.
Show answermore errors
What is the defining feature of a high-alert medication?
Show answerIt carries a heightened risk of causing significant patient harm if used in error
Which high-alert drug class includes heparin and warfarin?
Show answerAnticoagulants (antithrombotic agents)
Why is insulin classified as a high-alert medication?
Show answerDosing errors or mix-ups between insulin types can cause severe, rapid hypoglycemia
Why are neuromuscular blocking agents classified as high-alert?
Show answerThey cause respiratory paralysis and can be fatal without ventilatory support
What must be in place before giving a neuromuscular blocking agent?
Show answerA secured airway with ventilatory support
Where should concentrated potassium chloride vials generally not be stored?
Show answerIn patient care unit floor stock
What is an independent double-check?
Show answerA second qualified clinician separately verifies the drug, dose, and pump settings before administration
During an independent double-check, should the second nurse see the first nurse's calculation before checking?
Show answerNo, the second nurse should calculate independently first
Name the three things typically verified during an independent double-check of an IV opioid infusion.
Show answerThe drug, the concentration/dose, and the pump rate/programming
What lab value monitors the therapeutic effect of unfractionated heparin?
Show answeraPTT (activated partial thromboplastin time)
What lab value monitors warfarin therapy?
Show answerINR (international normalized ratio)
What is the antidote for heparin overdose?
Show answerProtamine sulfate
What is the antidote for warfarin overdose?
Show answerVitamin K (phytonadione)

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