Contraceptives, SERMs, and hormone therapy drugs with mechanism of action, distinct from the diabetes and thyroid focus of the endocrine drugs deck.
38 cards · mixed cards · AI-written, checked twice. Edit anything.
- What is the primary mechanism by which combined oral contraceptives (COCs) prevent pregnancy?
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They suppress the LH surge, preventing ovulation.- Which hormone component of combined oral contraceptives thickens cervical mucus to impede sperm?
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The progestin component.- How do progestin-only pills prevent pregnancy?
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By thickening cervical mucus and thinning the endometrium.- Leuprolide belongs to what drug class?
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GnRH agonist.- What happens to gonadotropin release with continuous, non-pulsatile GnRH agonist therapy?
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GnRH receptors downregulate, suppressing LH and FSH release.- What is the flare effect seen at the start of GnRH agonist therapy?
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A transient rise in testosterone or estrogen before sustained hormone suppression occurs.- Leuprolide is used in the treatment of which cancer?
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Prostate cancer.- Besides prostate cancer, leuprolide is used to treat which gynecologic condition?
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Endometriosis.- Ganirelix and cetrorelix belong to what drug class?
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GnRH antagonists.- What is the main clinical use of GnRH antagonists such as ganirelix?
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Preventing a premature LH surge during controlled ovarian stimulation for IVF.- What is the mechanism of action of mifepristone?
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It is a progesterone receptor antagonist.- What is the main clinical use of mifepristone?
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Medical abortion, given together with misoprostol.- What role does misoprostol play in medical abortion regimens?
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As a prostaglandin E1 analog, it ripens the cervix and induces uterine contractions.- What is the mechanism of action of ulipristal acetate?
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It is a selective progesterone receptor modulator.- What is the main clinical use of ulipristal acetate?
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Emergency contraception.
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