Crohn disease and ulcerative colitis distinguishing features, complications, and extraintestinal manifestations tested on USMLE Step 1.
34 cards · basic cards · AI-written, checked twice. Edit anything.
- Which IBD can affect any part of the GI tract from mouth to anus?
- Crohn disease
- Which IBD is characterized by skip lesions (patchy, discontinuous areas of involvement)?
- Crohn disease
- What is the most commonly affected site in Crohn disease?
- Terminal ileum
- Crohn disease inflammation extends through which layers of the bowel wall?
- All layers (transmural)
- What mucosal appearance, resembling street paving stones, is seen in Crohn disease?
- Cobblestone mucosa
- What term describes mesenteric fat wrapping around the bowel wall in Crohn disease?
- Creeping fat
- What histologic hallmark, though not always present, is classic for Crohn disease?
- Noncaseating granulomas
- What radiographic sign on barium studies reflects a narrowed, strictured bowel segment in Crohn disease?
- String sign
- Which IBD is more commonly associated with fistula formation?
- Crohn disease
- Which IBD more commonly causes bowel strictures and obstruction?
- Crohn disease
- Why can Crohn disease involving the terminal ileum cause vitamin B12 deficiency?
- The terminal ileum is the site of B12 absorption and is damaged or resected in Crohn disease
- Which IBD commonly causes perianal disease such as fissures, fistulas, and abscesses?
- Crohn disease
- How does smoking affect Crohn disease?
- Smoking increases the risk of and worsens Crohn disease
- Crohn disease increases the risk of which type of kidney stone?
- Calcium oxalate stones
- Why does Crohn disease increase the risk of calcium oxalate kidney stones?
- Fat malabsorption lets calcium bind fat instead of oxalate, leaving more free oxalate to be absorbed and excreted