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Gastroenterology · USMLE Step 1 · Healthcare and Nursing

USMLE Rapid Review: GI and Endocrine

A condensed rapid review pass over the highest yield gastrointestinal and endocrine facts for final week review.

About this set

39 basic cards for USMLE Step 1 Gastroenterology. It opens with "What GI hormone-secreting tumor causes recurrent, often multiple peptic ulcers" and "What is the most common infectious cause of duodenal ulcers?". Study it alongside the other USMLE Step 1 sets below.

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What GI hormone-secreting tumor causes recurrent, often multiple peptic ulcers by driving excess gastric acid?
Show answerGastrinoma (Zollinger-Ellison syndrome)
What is the most common infectious cause of duodenal ulcers?
Show answerHelicobacter pylori
By what mechanism do NSAIDs cause peptic ulcers?
Show answerThey inhibit COX enzymes, reducing protective prostaglandins in the gastric mucosa
What type of stress ulcer is associated with severe burns?
Show answerCurling ulcer
What type of stress ulcer is associated with increased intracranial pressure?
Show answerCushing ulcer
What esophageal emergency is a full-thickness (transmural) rupture, classically after forceful vomiting?
Show answerBoerhaave syndrome
What esophageal injury is a mucosal (partial-thickness) tear at the gastroesophageal junction from forceful vomiting?
Show answerMallory-Weiss tear
What esophageal change results from chronic GERD causing metaplasia from squamous to columnar epithelium?
Show answerBarrett esophagus
What esophageal motility disorder is caused by failure of lower esophageal sphincter relaxation from loss of myenteric plexus neurons?
Show answerAchalasia
Plummer-Vinson syndrome triad: esophageal webs, iron deficiency anemia, and ____.
Show answerdysphagia
What are the two most common causes of acute pancreatitis?
Show answerGallstones and alcohol use
What physical exam finding is a palpable, non-tender, distended gallbladder with painless jaundice, suggesting pancreatic head cancer rather than gallstones?
Show answerCourvoisier sign
Charcot triad for ascending cholangitis: right upper quadrant pain, fever, and ____.
Show answerjaundice
Reynolds pentad adds hypotension and ____ to Charcot triad in suppurative cholangitis.
Show answeraltered mental status
Which antibody is most associated with celiac disease?
Show answerAnti-tissue transglutaminase (anti-tTG) antibody

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