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Hematology and Oncology · Clinical Oncology

Oncology: Solid Tumor Staging and Screening Guidelines

TNM staging basics and current screening guideline ages and intervals for common solid tumors (breast, colon, cervical, lung) in clinical practice.

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In the TNM cancer staging system, what does the T category describe?
The size and local extent of the primary tumor
In the TNM cancer staging system, what does the N category describe?
The extent of regional lymph node involvement
In the TNM cancer staging system, what does the M category describe?
The presence or absence of distant metastasis
What does a designation of Tis mean in TNM staging?
Carcinoma in situ, an early cancer that has not invaded beyond its original layer
What does T0 indicate in TNM staging?
No evidence of a primary tumor
What does N0 indicate in TNM staging?
No regional lymph node metastasis
What does M0 indicate in TNM staging?
No distant metastasis detected
What does M1 indicate in TNM staging?
Distant metastasis is present
As the T category number increases from T1 to T4, what does this generally reflect?
Increasing size or local extent of the primary tumor
Which two organizations jointly maintain the TNM cancer staging system?
The American Joint Committee on Cancer (AJCC) and the Union for International Cancer Control (UICC)
What does the abbreviation AJCC stand for?
American Joint Committee on Cancer
What does the abbreviation UICC stand for?
Union for International Cancer Control
In overall stage grouping, which stage is generally used for carcinoma in situ?
Stage 0
In overall stage grouping, which stage generally indicates distant metastatic disease?
Stage IV
What prefix is added before TNM to denote staging based on physical exam and imaging prior to treatment?
The c prefix, as in cTNM (clinical staging)

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