Acne grading and therapy including isotretinoin precautions, rosacea subtypes, alopecia types, and common nail disorders and signs of systemic disease.
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- What is the primary, initiating lesion of acne vulgaris?
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The comedone
- What is the common name for an open comedone?
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Blackhead
- What is the common name for a closed comedone?
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Whitehead
- What is the first-line treatment for mild acne?
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A topical retinoid, with or without benzoyl peroxide
- What is a standard treatment regimen for moderate acne?
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A topical retinoid plus benzoyl peroxide plus a topical or oral antibiotic
- What is the treatment of choice for severe nodulocystic acne?
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Oral isotretinoin
- Why is benzoyl peroxide often combined with a topical antibiotic in acne therapy?
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To prevent the development of bacterial antibiotic resistance
- What reproductive precaution is required before and during isotretinoin therapy?
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Use of two reliable forms of contraception, since isotretinoin is highly teratogenic
- What is the purpose of the iPLEDGE program?
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A risk management program that ensures patients on isotretinoin are not pregnant and use contraception during treatment
- What labs are routinely monitored during isotretinoin therapy?
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Lipid panel (triglycerides) and liver function tests
- What is the most common mucocutaneous side effect of isotretinoin?
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Cheilitis (dry, cracked lips) along with general skin and mucosal dryness
- Which antiandrogen medication is commonly used to treat hormonal acne in women?
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Spironolactone
- How is acne conglobata characterized?
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A severe form of acne with interconnecting nodules, abscesses, and sinus tracts, without systemic symptoms
- What are the key features of erythematotelangiectatic rosacea?
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Persistent central facial erythema, flushing, and telangiectasias
- What distinguishes papulopustular rosacea from acne vulgaris?
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Papules and pustules occur without comedones