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Clinical Laboratory Science · ASCP MLS/MLT

Clinical Laboratory Science: Hematology

Complete blood count components, red and white cell morphology, and anemia classification tested on ASCP hematology sections.

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What does CBC stand for?
Complete blood count
What is the normal adult hemoglobin range for males?
Approximately 13.5 to 17.5 g/dL
What is the normal adult hemoglobin range for females?
Approximately 12.0 to 15.5 g/dL
What does MCV measure?
The average volume of a single red blood cell
What does MCH measure?
The average amount of hemoglobin per red blood cell
What does MCHC measure?
The average concentration of hemoglobin within red blood cells
A high RDW value indicates what?
Increased variation in red blood cell size (anisocytosis)
What is the reticulocyte count used to assess?
Bone marrow's red blood cell production activity
Microcytic anemia is defined by what MCV finding?
A low MCV (small red blood cells)
Macrocytic anemia is defined by what MCV finding?
A high MCV (large red blood cells)
Normocytic anemia is defined by what MCV finding?
A normal MCV with a low red cell count or hemoglobin
What is the most common cause of microcytic anemia?
Iron deficiency anemia
Which vitamin deficiencies commonly cause macrocytic anemia?
Vitamin B12 and folate deficiency
What red cell shape is characteristic of hereditary spherocytosis?
Spherocytes (round cells lacking central pallor)
What red cell shape is characteristic of sickle cell disease?
Sickle-shaped (crescent) cells

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