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Neurology · USMLE Step 1 · Healthcare and Nursing

USMLE Neurology: Headache and Seizure Disorders

Primary headache syndromes and epilepsy classification with first-line treatment, distinct from the lesion-localization focus of USMLE Neuro.

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35 basic cards for USMLE Step 1 Neurology. Set 4 of 6 in USMLE Neurology. It opens with "How long does a typical untreated migraine attack last?" and "What is the classic pain quality and laterality of migraine headache?". Study it alongside the other USMLE Step 1 sets below.

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How long does a typical untreated migraine attack last?
Show answer4 to 72 hours
What is the classic pain quality and laterality of migraine headache?
Show answerUnilateral, throbbing (pulsating) pain
Which gastrointestinal symptom commonly accompanies a migraine attack?
Show answerNausea and vomiting
Which sensory symptoms commonly accompany a migraine attack?
Show answerPhotophobia and phonophobia
What is the most common visual aura symptom in migraine with aura?
Show answerScintillating scotoma (a shimmering, expanding visual disturbance)
What is the first-line abortive drug class for moderate to severe migraine attacks?
Show answerTriptans
What is the mechanism of action of triptans?
Show answerSelective agonists at serotonin 5-HT1B and 5-HT1D receptors, causing vasoconstriction
Triptans are contraindicated in patients with which condition?
Show answerCoronary artery disease or other vasospastic/ischemic conditions
Name a first-line beta-blocker used for migraine prophylaxis.
Show answerPropranolol
How is a tension-type headache classically described?
Show answerBilateral, band-like or pressing pain of mild to moderate intensity
What is the first-line treatment for tension-type headache?
Show answerNSAIDs or acetaminophen
How is cluster headache pain classically described?
Show answerSevere, unilateral periorbital or retro-orbital pain
What ipsilateral autonomic symptoms accompany cluster headache?
Show answerLacrimation, rhinorrhea, ptosis, miosis, and conjunctival injection
What is the first-line acute treatment for a cluster headache attack?
Show answer100% oxygen by mask
Which triptan formulation is used for acute treatment of cluster headache?
Show answerSubcutaneous sumatriptan

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