Benign and malignant bone tumors plus osteoporosis, osteomalacia, and Paget disease with their imaging and lab clues.
34 cards · basic cards · AI-written, checked twice. Edit anything.
- What is the most common benign bone tumor overall?
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Osteochondroma- What clinical feature is classic for osteoid osteoma?
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Night pain that is dramatically relieved by NSAIDs- How does osteoblastoma typically differ from osteoid osteoma?
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It is larger (over 2 cm) and most often occurs in the vertebrae- Where do giant cell tumors of bone typically arise?
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The epiphysis of long bones, often near the knee- What is the classic x-ray appearance of a giant cell tumor of bone?
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A soap bubble appearance- In what age group do giant cell tumors of bone most commonly occur?
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Young adults, roughly 20 to 40 years old- Where do enchondromas typically arise?
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In the medullary cavity of the small bones of the hands and feet- What is the characteristic x-ray finding in fibrous dysplasia?
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A ground-glass appearance- What syndrome pairs fibrous dysplasia with precocious puberty and cafe-au-lait spots?
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McCune-Albright syndrome- What is the most common primary malignant bone tumor?
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Osteosarcoma- Where does osteosarcoma most often arise?
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The metaphysis of long bones, especially around the knee (distal femur or proximal tibia)- What is the age distribution of osteosarcoma?
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Bimodal: adolescents during growth spurts, and older adults with predisposing conditions like Paget disease- What periosteal x-ray sign, from the tumor lifting the periosteum off the bone, is classic for osteosarcoma?
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Codman triangle- What radiating, spiculated periosteal pattern is seen in osteosarcoma?
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A sunburst pattern- Name three risk factors for developing osteosarcoma.
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Paget disease of bone, prior radiation exposure, and hereditary retinoblastoma (RB1 mutation)
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