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Respiratory Therapy · NBRC TMC

Respiratory Therapy: Pharmacology

Bronchodilators, corticosteroids, and other inhaled or aerosolized respiratory medications, including drug class and mechanism of action.

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Drug class of albuterol
Short-acting beta-2 agonist (SABA)
Mechanism of action of beta-2 agonists
Stimulating beta-2 receptors to relax bronchial smooth muscle and cause bronchodilation
Common side effect of beta-2 agonists
Tachycardia and tremor
Drug class of salmeterol and formoterol
Long-acting beta-2 agonist (LABA)
Drug class of ipratropium bromide
Short-acting anticholinergic (antimuscarinic) bronchodilator
Mechanism of action of anticholinergic bronchodilators
Blocking acetylcholine at muscarinic receptors to reduce bronchoconstriction and secretions
Drug class of tiotropium
Long-acting anticholinergic (antimuscarinic) bronchodilator
Combination bronchodilator pairing a SABA with a short-acting anticholinergic
Albuterol and ipratropium
Primary use of inhaled corticosteroids such as fluticasone or budesonide
Reducing airway inflammation for long-term asthma or COPD control
Inhaled corticosteroids are not used for
Acute bronchospasm relief, since they have no immediate bronchodilator effect
A key patient counseling point after inhaled corticosteroid use
Rinsing the mouth with water to reduce the risk of oral thrush
Drug class of theophylline
Methylxanthine bronchodilator
A key monitoring concern with theophylline
Narrow therapeutic index requiring blood level monitoring to avoid toxicity
Mechanism of action of leukotriene modifiers such as montelukast
Blocking leukotriene receptors to reduce airway inflammation and bronchoconstriction
Drug class of cromolyn sodium
Mast cell stabilizer

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