Nursing Pharmacology · NCLEX-RN

NCLEX Pharmacology

Nursing-relevant drug classes with the single most important nursing consideration or side effect to watch for.

44 cards · basic cards · AI-written, checked twice. Edit anything.

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What is the primary nursing consideration when administering ACE inhibitors?
Monitor serum potassium levels; ACE inhibitors increase potassium retention and can cause hyperkalemia
What major electrolyte imbalance should be monitored with ARB medications?
Hyperkalemia; ARBs block angiotensin II receptors, reducing aldosterone secretion
What is the most important vital sign to monitor when giving beta blockers?
Heart rate; watch for bradycardia and decreased cardiac output
What compensatory response can occur with dihydropyridine calcium channel blockers?
Reflex tachycardia; peripheral vasodilation triggers compensatory heart rate increase
What is the most critical electrolyte disturbance from loop diuretics?
Hypokalemia; loop diuretics inhibit sodium, chloride, and potassium reabsorption at the thick ascending limb of the loop of Henle, causing potassium wasting.
What electrolyte imbalance is most commonly associated with thiazide diuretics?
Hypokalemia; they increase distal tubular secretion of potassium into the urine
Why should patients on spironolactone be monitored for hyperkalemia?
Spironolactone blocks aldosterone, preventing potassium excretion in the distal tubule
What drug-related muscle problem should patients on statins report immediately?
Muscle pain, weakness, or dark urine; signs of statin-induced myopathy or rhabdomyolysis
What is the most serious GI complication associated with NSAID use?
Gastrointestinal bleeding and ulceration; NSAIDs inhibit prostaglandins that protect gastric mucosa
What is the most important consideration when administering acetaminophen?
Monitor total daily dose to prevent hepatotoxicity; maximum 4 grams per day in adults
What is the major nursing consideration for patients on aspirin therapy?
Monitor for bleeding; aspirin irreversibly inhibits platelet aggregation
What is the most critical monitoring parameter for warfarin therapy?
INR (International Normalized Ratio); maintain within therapeutic range to prevent bleeding or clotting
What serious adverse reaction should be monitored when administering IV heparin?
Heparin-induced thrombocytopenia (HIT); platelet count may drop significantly, requiring drug discontinuation
Why is renal function critical when monitoring DOAC therapy?
DOACs are renally eliminated; decreased renal function increases drug levels and bleeding risk
What is the main nursing concern when administering clopidogrel (Plavix)?
Bleeding risk; clopidogrel irreversibly inhibits platelet aggregation like aspirin

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