Nursing Pharmacology · NCLEX-RN

Nursing Pharmacology: Endocrine Medications

Insulin types, oral hypoglycemics, and thyroid medications with their onset, peak, and hypoglycemia recognition teaching points.

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Which three insulins are classified as rapid-acting?
Lispro, aspart, and glulisine
What is the onset of rapid-acting insulin (lispro, aspart, glulisine)?
10-15 minutes
What is the peak of rapid-acting insulin?
1-2 hours
What is the duration of action of rapid-acting insulin?
3-5 hours
When should a patient inject rapid-acting insulin relative to a meal?
Within 15 minutes before eating, with food ready to eat right away
What is the onset of regular (short-acting) insulin?
30 minutes to 1 hour
What is the peak of regular insulin?
2-4 hours
What is the duration of action of regular insulin?
5-8 hours
Which type of insulin is the only one safe to give intravenously?
Regular insulin
What is the onset of NPH (intermediate-acting) insulin?
1-2 hours
What is the peak of NPH insulin?
4-12 hours
What is the duration of action of NPH insulin?
14-24 hours
What is the onset of long-acting insulin (glargine, detemir)?
1-2 hours
Insulin glargine must never be ____ with another insulin in the same syringe.
mixed
What are the early, adrenergic signs of hypoglycemia?
Shakiness, sweating, tachycardia, hunger, and anxiety

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