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Nursing · NCLEX-RN

Nursing Genetics and Genomics

Genetic screening indications and genetic counseling referral concepts within nursing practice, distinct from the diagnostic focus of USMLE medical genetics content.

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What is the primary role of a bedside nurse when a patient has genetic risk factors?
Identify the risk and refer the patient to a genetic counselor.
What tool do nurses use to identify hereditary risk patterns in a patient's family?
A three-generation pedigree (family history).
What maternal age is generally considered a genetic screening indication in pregnancy?
35 years or older.
What is the purpose of newborn screening?
To detect treatable metabolic and genetic conditions before symptoms appear.
When is the newborn screening blood sample typically collected?
24 to 48 hours after birth.
Name a classic condition included on the newborn screening panel.
Phenylketonuria (PKU).
What federal law protects patients from discrimination based on genetic information in health insurance and employment?
The Genetic Information Nondiscrimination Act (GINA).
What ethical principle means a genetic counselor presents facts without pushing the patient toward a decision?
Nondirective counseling.
What is the key difference between a genetic screening test and a diagnostic test?
Screening estimates risk; a diagnostic test confirms whether the condition is present.
What should a nurse do when a patient's genetic screening result is positive?
Refer the patient for diagnostic testing and genetic counseling.
What is cascade testing?
Testing biological relatives of a person with a confirmed genetic condition.
What family cancer history finding should prompt a referral for genetic counseling?
Multiple relatives with the same type of cancer diagnosed at an early age.
What is consanguinity?
A blood relationship between two parents, such as first cousins.
Why is consanguinity a genetic screening indication?
It increases the risk of recessive genetic disorders in offspring.
Which ethnic group has an increased carrier risk for Tay-Sachs disease?
People of Ashkenazi Jewish descent.

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