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NAPLEX · NAPLEX · Healthcare and Nursing

NAPLEX Compounding and Calculations

Pharmacist-level sterile and non-sterile compounding concepts and pharmacy calculations tested on the NAPLEX, distinct from the technician-scope PTCB compounding deck.

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40 mixed cards for NAPLEX NAPLEX. It opens with "What calculation method is used to determine the proportions of two components" and "Using alligation alternate to prepare 100 mL of a 6% solution from a 10% stock". More Healthcare and Nursing decks are listed below.

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What calculation method is used to determine the proportions of two components of different strengths needed to prepare a mixture of a desired intermediate strength?
Show answerAlligation (alternate)
Using alligation alternate to prepare 100 mL of a 6% solution from a 10% stock solution and a 2% stock solution requires ____ of the 10% stock.
Show answer50 mL
What is the formula for specific gravity?
Show answerSpecific gravity = weight of substance / weight of an equal volume of water
In compounding, when is the aliquot method used?
Show answerWhen the desired quantity of an ingredient is smaller than the smallest amount that can be accurately weighed or measured on the available equipment
What is the formula for least weighable quantity (LWQ) on a balance?
Show answerLWQ = balance sensitivity requirement / acceptable percent error (as a decimal)
On a balance with a sensitivity requirement of 6 mg and a desired accuracy of 5% error, the least weighable quantity is ____.
Show answer120 mg
What is the formula relating milliequivalents (mEq) to milligrams?
Show answermEq = (mg x valence) / molecular weight
Since sodium chloride has a molecular weight of 58.5 g/mol and a valence of 1, one milliequivalent of sodium chloride equals ____.
Show answer58.5 mg
What is the formula for calculating osmolarity of a solution in mOsmol/L?
Show answermOsmol/L = (concentration in g/L / molecular weight) x number of particle species x 1000
What is the purpose of the sodium chloride equivalent method?
Show answerTo determine the amount of NaCl or diluent needed to make a compounded solution isotonic with body fluids
In the freezing point depression method for isotonicity, what freezing point is used as the reference for body fluids?
Show answer-0.52 degrees C
What is Clark's Rule for pediatric dosing?
Show answerChild dose = (child's weight in lb / 150) x adult dose
What is Young's Rule for pediatric dosing?
Show answerChild dose = (age in years / (age + 12)) x adult dose
What is the Mosteller formula for body surface area (BSA)?
Show answerBSA in m2 = square root of [(height in cm x weight in kg) / 3600]
What is the Cockcroft-Gault equation for creatinine clearance?
Show answerCrCl (mL/min) = [(140 - age) x weight in kg] / (72 x serum creatinine in mg/dL), multiplied by 0.85 for females

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