Pharmacist-level sterile and non-sterile compounding concepts and pharmacy calculations tested on the NAPLEX, distinct from the technician-scope PTCB compounding deck.
40 cards · basic cards · AI-written, checked twice. Edit anything.
- What calculation method is used to determine the proportions of two components of different strengths needed to prepare a mixture of a desired intermediate strength?
- Alligation (alternate)
- Using alligation alternate to prepare 100 mL of a 6% solution from a 10% stock solution and a 2% stock solution requires ____ of the 10% stock.
- 50 mL
- What is the formula for specific gravity?
- Specific gravity = weight of substance / weight of an equal volume of water
- In compounding, when is the aliquot method used?
- When the desired quantity of an ingredient is smaller than the smallest amount that can be accurately weighed or measured on the available equipment
- What is the formula for least weighable quantity (LWQ) on a balance?
- LWQ = balance sensitivity requirement / acceptable percent error (as a decimal)
- On a balance with a sensitivity requirement of 6 mg and a desired accuracy of 5% error, the least weighable quantity is ____.
- 120 mg
- What is the formula relating milliequivalents (mEq) to milligrams?
- mEq = (mg x valence) / molecular weight
- Since sodium chloride has a molecular weight of 58.5 g/mol and a valence of 1, one milliequivalent of sodium chloride equals ____.
- 58.5 mg
- What is the formula for calculating osmolarity of a solution in mOsmol/L?
- mOsmol/L = (concentration in g/L / molecular weight) x number of particle species x 1000
- What is the purpose of the sodium chloride equivalent method?
- To determine the amount of NaCl or diluent needed to make a compounded solution isotonic with body fluids
- In the freezing point depression method for isotonicity, what freezing point is used as the reference for body fluids?
- -0.52 degrees C
- What is Clark's Rule for pediatric dosing?
- Child dose = (child's weight in lb / 150) x adult dose
- What is Young's Rule for pediatric dosing?
- Child dose = (age in years / (age + 12)) x adult dose
- What is the Mosteller formula for body surface area (BSA)?
- BSA in m2 = square root of [(height in cm x weight in kg) / 3600]
- What is the Cockcroft-Gault equation for creatinine clearance?
- CrCl (mL/min) = [(140 - age) x weight in kg] / (72 x serum creatinine in mg/dL), multiplied by 0.85 for females