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Obstetrics and Gynecology · USMLE Step 2 CK

USMLE Step 2 CK Gynecology: Breast Disease

Benign and malignant breast disease workup and screening mammography scenarios tested on USMLE Step 2 CK.

30 cards · basic cards · AI-written, checked twice. Edit anything.

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At what age should average-risk women begin biennial screening mammography per current USPSTF guidance?
Age 40
What is the most common benign breast tumor in women under 30?
Fibroadenoma
What benign breast condition causes bilateral, cyclic breast pain and lumpiness that fluctuates with the menstrual cycle?
Fibrocystic breast changes
How is an asymptomatic simple breast cyst confirmed by ultrasound typically managed?
Observation, no aspiration or biopsy needed
What benign breast lesion follows trauma or surgery and can mimic cancer on exam and imaging?
Fat necrosis
What benign breast lesion is the most common cause of unilateral bloody nipple discharge?
Intraductal papilloma
What organism most commonly causes lactational mastitis?
Staphylococcus aureus
Should breastfeeding or pumping continue during lactational mastitis?
Yes, continued breastfeeding or pumping is recommended
What is the next step when a fluctuant, tender breast mass develops during treatment for mastitis?
Ultrasound to evaluate for abscess, then drainage if present
What breast condition presents as a unilateral eczematous, scaly nipple lesion associated with underlying ductal carcinoma?
Paget disease of the breast
What aggressive breast cancer presents with skin edema, erythema, and peau d'orange, often without a discrete mass?
Inflammatory breast cancer
What is the most common histologic type of invasive breast cancer overall?
Invasive ductal carcinoma
Which invasive breast cancer subtype is more often bilateral and multicentric and harder to detect on mammography?
Invasive lobular carcinoma
Ductal carcinoma in situ (DCIS) is malignant ductal epithelial proliferation confined within the ____, without invasion.
basement membrane
Is lobular carcinoma in situ (LCIS) typically visible as a mass on breast imaging?
No, it is usually an incidental finding on biopsy, not visible on imaging

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