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Physiology · USMLE Step 1 · Healthcare and Nursing

USMLE Physiology: Gastrointestinal Physiology

GI hormone regulation, motility mechanisms, and digestive and absorptive processes tested on USMLE Step 1.

About this set

34 basic cards for USMLE Step 1 Physiology. Set 4 of 9 in USMLE Physiology. It opens with "Where are gastrin-secreting G cells located?" and "What is the primary action of gastrin?". Study it alongside the other USMLE Step 1 sets below.

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Where are gastrin-secreting G cells located?
Show answerAntrum of the stomach
What is the primary action of gastrin?
Show answerStimulates parietal cells to secrete HCl (gastric acid)
What stimulates gastrin secretion?
Show answerVagal stimulation, stomach distention, and luminal peptides/amino acids
Where are CCK-secreting I cells located?
Show answerDuodenum and jejunum
What effect does CCK have on the gallbladder?
Show answerStimulates gallbladder contraction
What effect does CCK have on the pancreas?
Show answerStimulates secretion of pancreatic digestive enzymes
What stimulates CCK secretion?
Show answerFatty acids and amino acids in the duodenum
Where are secretin-secreting S cells located?
Show answerDuodenum
What effect does secretin have on the pancreas?
Show answerStimulates secretion of bicarbonate-rich fluid from pancreatic ducts
What effect does secretin have on gastric acid secretion?
Show answerInhibits it
What stimulates secretin secretion?
Show answerAcid (low pH) in the duodenum
What is the main effect of GIP (glucose-dependent insulinotropic peptide)?
Show answerStimulates insulin release from the pancreas
What is the main function of motilin?
Show answerStimulates migrating motor complexes during fasting
What is the main function of somatostatin in the GI tract?
Show answerInhibits secretion of gastric acid and virtually all other GI hormones
What is the main action of vasoactive intestinal peptide (VIP)?
Show answerRelaxes GI smooth muscle and sphincters, and stimulates intestinal secretion

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